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ADA adenosine deaminase [ Gallus gallus (chicken) ]

Gene ID: 419194, updated on 20-Jun-2018

Summary

Symbol
ADAprovided by CGNC
Full Name
adenosine deaminaseprovided by CGNC
Primary source
CGNC:3060
See related
Ensembl:ENSGALG00000004170
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs

Genomic context

See ADA in Genome Data Viewer
Location:
chromosome: 20
Exon count:
11
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 20 NC_006107.5 (5355077..5367713)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 20 NC_006107.4 (5501132..5513768)

Chromosome 20 - NC_006107.5Genomic Context describing neighboring genes Neighboring gene regulating synaptic membrane exocytosis 4 Neighboring gene potassium two pore domain channel subfamily K member 15 Neighboring gene WNT1 inducible signaling pathway protein 2 Neighboring gene uncharacterized LOC101747703 Neighboring gene protein kinase (cAMP-dependent, catalytic) inhibitor gamma Neighboring gene serine incorporator 3

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
adenosine deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
adenosine deaminase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
T cell activation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
adenosine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
adenosine catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
hypoxanthine salvage IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inosine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inosine biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of adenosine receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleotide metabolic process IEA
Inferred from Electronic Annotation
more info
 
purine ribonucleoside monophosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell junction IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle lumen IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lysosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
adenosine deaminase
Names
adenosine aminohydrolase
NP_001006290.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006290.2NP_001006290.1  adenosine deaminase

    See identical proteins and their annotated locations for NP_001006290.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ720038
    UniProtKB/Swiss-Prot
    Q5ZKP6
    Related
    ENSGALP00000006620.4, ENSGALT00000006631.4
    Conserved Domains (1) summary
    cd01320
    Location:11343
    ADA; Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006107.5 Reference GRCg6a Primary Assembly

    Range
    5355077..5367713
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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