Format

Send to:

Choose Destination

nsl1 non-specific lethal 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41911, updated on 5-Nov-2017
Official Symbol
nsl1provided by FlyBase
Official Full Name
non-specific lethal 1provided by FlyBase
Primary source
FLYBASE:FBgn0262527
Locus tag
Dmel_CG4699
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4699; Dmel\CG4699; E(nos); l(3)06536; l(3)S009413; Nsl1; NSL1; wah
Location:
89A4-89A5
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15793782..15802102)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11619504..11627824)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene CG9589 gene product from transcript CG9589-RA Neighboring gene crossover suppressor on 3 of Gowen Neighboring gene Acylphosphatase 2 Neighboring gene alpha-Mannosidase class II b Neighboring gene CG9593 gene product from transcript CG9593-RB Neighboring gene ncRNA Neighboring gene ncRNA

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
core promoter binding IDA
Inferred from Direct Assay
more info
PubMed 
histone acetyltransferase binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
germ-line stem cell population maintenance IGI
Inferred from Genetic Interaction
more info
PubMed 
germarium-derived female germ-line cyst formation IGI
Inferred from Genetic Interaction
more info
PubMed 
larval somatic muscle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic G2 DNA damage checkpoint IGI
Inferred from Genetic Interaction
more info
PubMed 
neuromuscular junction development IMP
Inferred from Mutant Phenotype
more info
PubMed 
oogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
NSL complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
polytene chromosome interband IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
CG4699 gene product from transcript CG4699-RP
Names
CG4699-PD
CG4699-PE
CG4699-PF
CG4699-PH
CG4699-PI
CG4699-PJ
CG4699-PK
CG4699-PL
CG4699-PM
CG4699-PN
CG4699-PO
CG4699-PP
lethal (3) 06536
non-specific lethal 1
nonspecific lethal 1
nsl1-PD
nsl1-PE
nsl1-PF
nsl1-PH
nsl1-PI
nsl1-PJ
nsl1-PK
nsl1-PL
nsl1-PM
nsl1-PN
nsl1-PO
nsl1-PP
waharan

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    15793782..15802102
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275684.1NP_001262613.1  non-specific lethal 1, isoform P [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262613.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JIM0
    Related
    FBpp0306659.1, FBtr0334592
    Conserved Domains (1) summary
    pfam15275
    Location:12291304
    PEHE; PEHE domain
  2. NM_001170151.3NP_001163622.1  non-specific lethal 1, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163622.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JIM0
    Related
    FBpp0290941.1, FBtr0301727
    Conserved Domains (1) summary
    pfam15275
    Location:12291304
    PEHE; PEHE domain
  3. NM_001170152.2NP_001163623.1  non-specific lethal 1, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163623.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A4V2Z1
    Related
    FBpp0290944.1, FBtr0301730
    Conserved Domains (1) summary
    pfam15275
    Location:12301305
    PEHE; PEHE domain
  4. NM_001260197.2NP_001247126.1  non-specific lethal 1, isoform O [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247126.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K690
    Related
    FBpp0301597.1, FBtr0309863
    Conserved Domains (1) summary
    pfam15275
    Location:12311306
    PEHE; PEHE domain
  5. NM_142235.4NP_650492.2  non-specific lethal 1, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650492.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KI68
    Related
    FBpp0290942.1, FBtr0301728
    Conserved Domains (1) summary
    pfam15275
    Location:12281303
    PEHE; PEHE domain
  6. NM_001170153.3NP_001163624.1  non-specific lethal 1, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163624.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JIM1
    Related
    FBpp0290946.1, FBtr0301732
    Conserved Domains (1) summary
    PRK08581
    Location:100323
    PRK08581; N-acetylmuramoyl-L-alanine amidase; Validated
  7. NM_001260195.2NP_001247124.1  non-specific lethal 1, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247124.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K6Z4
    Related
    FBpp0301594.1, FBtr0309860
    Conserved Domains (1) summary
    PRK08581
    Location:100323
    PRK08581; N-acetylmuramoyl-L-alanine amidase; Validated
  8. NM_169673.3NP_732070.2  non-specific lethal 1, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732070.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A4V2Z1
    Related
    FBpp0290945.1, FBtr0301731
    Conserved Domains (1) summary
    pfam15275
    Location:12301305
    PEHE; PEHE domain
  9. NM_169672.4NP_732069.3  non-specific lethal 1, isoform M [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732069.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    E2QD16
    Related
    FBpp0301595.1, FBtr0309861
    Conserved Domains (1) summary
    pfam15275
    Location:12501325
    PEHE; PEHE domain
  10. NM_001260194.2NP_001247123.1  non-specific lethal 1, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247123.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K6I8
    Related
    FBpp0301593.1, FBtr0309859
    Conserved Domains (1) summary
    PRK08581
    Location:100323
    PRK08581; N-acetylmuramoyl-L-alanine amidase; Validated
  11. NM_001260196.2NP_001247125.1  non-specific lethal 1, isoform N [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247125.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K663
    Related
    FBpp0301596.1, FBtr0309862
    Conserved Domains (1) summary
    pfam15275
    Location:12491324
    PEHE; PEHE domain
  12. NM_001170150.3NP_001163621.1  non-specific lethal 1, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163621.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A4V2Z1
    Related
    FBpp0290940.1, FBtr0301726
    Conserved Domains (1) summary
    pfam15275
    Location:12301305
    PEHE; PEHE domain
Support Center