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ESD esterase D [ Gallus gallus (chicken) ]

Gene ID: 418856, updated on 13-Apr-2026
Symbol
ESDprovided by CGNC
Full Name
esterase Dprovided by CGNC
Primary source
CGNC:12753
See related
Ensembl:ENSGALG00010003848
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See ESD in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (168205188..168214675, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (168293874..168303381, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene rubicon like autophagy enhancer Neighboring gene leucine rich repeats and calponin homology domain containing 1 Neighboring gene 5-hydroxytryptamine receptor 2A Neighboring gene uncharacterized LOC124417625

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables S-formylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in formaldehyde catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
S-formylglutathione hydrolase
Names
esterase D/formylglutathione hydrolase
NP_001264720.1
NP_001264721.1
NP_001264722.1
XP_025006132.1
XP_046764182.1
XP_046764183.1
XP_046764184.1
XP_046764185.1
XP_046764186.1
XP_046764187.1
XP_046797578.1
XP_046797579.1
XP_046797582.1
XP_046797586.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277791.2NP_001264720.1  S-formylglutathione hydrolase

    See identical proteins and their annotated locations for NP_001264720.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
    Source sequence(s)
    JAENSK010000027
    UniProtKB/TrEMBL
    A0A8V0XAV4
    Conserved Domains (1) summary
    PLN02442
    Location:2281
    PLN02442; S-formylglutathione hydrolase
  2. NM_001277792.2NP_001264721.1  S-formylglutathione hydrolase

    See identical proteins and their annotated locations for NP_001264721.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    JAENSK010000027
    UniProtKB/TrEMBL
    A0A8V0XAV4
    Conserved Domains (1) summary
    PLN02442
    Location:2281
    PLN02442; S-formylglutathione hydrolase
  3. NM_001277793.2NP_001264722.1  S-formylglutathione hydrolase

    See identical proteins and their annotated locations for NP_001264722.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    JAENSK010000027
    UniProtKB/TrEMBL
    A0A8V0XAV4
    Related
    ENSGALP00010005250.1, ENSGALT00010008906.1
    Conserved Domains (1) summary
    PLN02442
    Location:2281
    PLN02442; S-formylglutathione hydrolase

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    168205188..168214675 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046941626.1XP_046797582.1  S-formylglutathione hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A8V0XAV4
  2. XM_046941623.1XP_046797579.1  S-formylglutathione hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A8V0XAV4
  3. XM_046941630.1XP_046797586.1  S-formylglutathione hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A8V0XAV4
  4. XM_046941622.1XP_046797578.1  S-formylglutathione hydrolase isoform X1

    UniProtKB/TrEMBL
    A0A8V0XAV4
  5. XM_025150364.3XP_025006132.1  S-formylglutathione hydrolase isoform X1

    UniProtKB/TrEMBL
    A0A8V0XAV4
    Conserved Domains (1) summary
    PLN02442
    Location:2281
    PLN02442; S-formylglutathione hydrolase

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    168293874..168303381 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046908229.1XP_046764185.1  S-formylglutathione hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A8V0XAV4
  2. XM_046908228.1XP_046764184.1  S-formylglutathione hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A8V0XAV4
  3. XM_046908231.1XP_046764187.1  S-formylglutathione hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A8V0XAV4
  4. XM_046908230.1XP_046764186.1  S-formylglutathione hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A8V0XAV4
  5. XM_046908227.1XP_046764183.1  S-formylglutathione hydrolase isoform X1

    UniProtKB/TrEMBL
    A0A8V0XAV4
  6. XM_046908226.1XP_046764182.1  S-formylglutathione hydrolase isoform X1

    UniProtKB/TrEMBL
    A0A8V0XAV4