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CG6125 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41882, updated on 4-Jan-2025

Summary

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Official Symbol
CG6125provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038337
Locus tag
Dmel_CG6125
See related
AllianceGenome:FB:FBgn0038337
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6125
Summary
Predicted to enable sulfate transmembrane transporter activity. Predicted to be involved in chloride transmembrane transport and sulfate transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head; amnioserosa; embryonic large intestine; and yolk nucleus. Orthologous to human SLC26A11 (solute carrier family 26 member 11). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG6125 in Genome Data Viewer
Location:
88F4-88F4; 3-57 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15402598..15407070, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11228320..11232792, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cerebral cavernous malformation 3 Neighboring gene RIM-binding protein Neighboring gene heineken-cup Neighboring gene antisense RNA:CR46058 Neighboring gene Ataxin-2 Neighboring gene long non-coding RNA:CR45911 Neighboring gene mir-13b-1 stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ion and solute transport by Prestin in Drosophila and Anopheles. Hirata T, et al. J Insect Physiol, 2012 Apr. PMID 22321763, Free PMC Article
  2. Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster. Ringrose L, et al. Dev Cell, 2003 Nov. PMID 14602076
  3. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204
  4. Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. Weber AL, et al. PLoS One, 2012. PMID 22496853, Free PMC Article
  5. Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. Broderick NA, et al. mBio, 2014 May 27. PMID 24865556, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables sulfate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chloride transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sulfate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6125-PA
CG6125-PB
CG6125-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    15402598..15407070 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300409.1 → NP_001287338.1  uncharacterized protein Dmel_CG6125, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287338.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IGY4, Q8SYW1
    Conserved Domains (2) summary
    TIGR00815
    Location:58 → 591
    sulP; high affinity sulphate transporter 1
    cl00604
    Location:501 → 579
    STAS; Sulphate Transporter and Anti-Sigma factor antagonist domain found in the C-terminal region of sulphate transporters as well as in bacterial and archaeal proteins involved in the regulation of sigma factors

  2. NM_142208.3 → NP_650465.1  uncharacterized protein Dmel_CG6125, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650465.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IGY4, Q8SYW1
    Related
    FBpp0082559
    Conserved Domains (2) summary
    TIGR00815
    Location:58 → 591
    sulP; high affinity sulphate transporter 1
    cl00604
    Location:501 → 579
    STAS; Sulphate Transporter and Anti-Sigma factor antagonist domain found in the C-terminal region of sulphate transporters as well as in bacterial and archaeal proteins involved in the regulation of sigma factors

  3. NM_169656.2 → NP_732032.1  uncharacterized protein Dmel_CG6125, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732032.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IGY4, Q9VF65
    Related
    FBpp0082560
    Conserved Domains (3) summary
    TIGR00815
    Location:87 → 620
    sulP; high affinity sulphate transporter 1
    cl00604
    Location:530 → 608
    STAS; Sulphate Transporter and Anti-Sigma factor antagonist domain found in the C-terminal region of sulphate transporters as well as in bacterial and archaeal proteins involved in the regulation of sigma factors
    cl23746
    Location:108 → 462
    HCO3_cotransp; HCO3- transporter family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IGY4 Q8IGY4
Q8SYW1 Q8SYW1
Q9VF65 Q9VF65

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