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IL18R1 interleukin 18 receptor 1 [ Gallus gallus (chicken) ]

Gene ID: 418717, updated on 5-Sep-2025
Official Symbol
IL18R1provided by CGNC
Official Full Name
interleukin 18 receptor 1provided by CGNC
Primary source
CGNC:12591
See related
Ensembl:ENSGALG00010013836
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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See IL18R1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (134010265..134029557)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (133968354..133986406)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene interleukin 1 receptor like 2 Neighboring gene interleukin 1 receptor like 1 Neighboring gene interleukin 18 receptor accessory protein Neighboring gene solute carrier family 9 member A4 Neighboring gene uncharacterized LOC121109155

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables interleukin-1 receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-18 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-18 receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interleukin-18-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of type II interferon production IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
interleukin-18 receptor 1
Names
IL-18 receptor alpha
NP_001138697.3
NP_001384128.1
NP_001384129.1
NP_001384130.1
XP_040555074.1
XP_040555076.1
XP_040555080.1
XP_046764021.1
XP_046764022.1
XP_046764023.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145225.3 → NP_001138697.3  interleukin-18 receptor 1 isoform a precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000025
    UniProtKB/TrEMBL
    A0A8V0YLY8, B8PQ41
    Related
    ENSGALP00010019624.1, ENSGALT00010033212.1
    Conserved Domains (3) summary
    PHA02785
    Location:24 → 306
    PHA02785; IL-beta-binding protein; Provisional
    smart00255
    Location:381 → 530
    TIR; Toll - interleukin 1 - resistance
    cl11960
    Location:136 → 185
    Ig; Immunoglobulin domain

  2. NM_001397199.1 → NP_001384128.1  interleukin-18 receptor 1 isoform a precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000025
    UniProtKB/TrEMBL
    A0A8V0YLY8, B8PQ41
    Conserved Domains (3) summary
    PHA02785
    Location:24 → 306
    PHA02785; IL-beta-binding protein; Provisional
    smart00255
    Location:381 → 530
    TIR; Toll - interleukin 1 - resistance
    cl11960
    Location:136 → 185
    Ig; Immunoglobulin domain

  3. NM_001397200.1 → NP_001384129.1  interleukin-18 receptor 1 isoform a precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000025
    UniProtKB/TrEMBL
    A0A8V0YLY8, B8PQ41
    Conserved Domains (3) summary
    PHA02785
    Location:24 → 306
    PHA02785; IL-beta-binding protein; Provisional
    smart00255
    Location:381 → 530
    TIR; Toll - interleukin 1 - resistance
    cl11960
    Location:136 → 185
    Ig; Immunoglobulin domain

  4. NM_001397201.1 → NP_001384130.1  interleukin-18 receptor 1 isoform b

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000025
    UniProtKB/TrEMBL
    B8PQ41
    Conserved Domains (3) summary
    PHA02785
    Location:67 → 231
    PHA02785; IL-beta-binding protein; Provisional
    smart00255
    Location:306 → 455
    TIR; Toll - interleukin 1 - resistance
    cl11960
    Location:61 → 110
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    134010265..134029557
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040699142.2 → XP_040555076.1  interleukin-18 receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YLY8, B8PQ41
    Conserved Domains (3) summary
    PHA02785
    Location:24 → 306
    PHA02785; IL-beta-binding protein; Provisional
    smart00255
    Location:381 → 530
    TIR; Toll - interleukin 1 - resistance
    cl11960
    Location:136 → 185
    Ig; Immunoglobulin domain

  2. XM_040699146.2 → XP_040555080.1  interleukin-18 receptor 1 isoform X2

    UniProtKB/TrEMBL
    B8PQ41
    Conserved Domains (3) summary
    PHA02785
    Location:67 → 231
    PHA02785; IL-beta-binding protein; Provisional
    smart00255
    Location:306 → 455
    TIR; Toll - interleukin 1 - resistance
    cl11960
    Location:61 → 110
    Ig; Immunoglobulin domain

  3. XM_040699140.2 → XP_040555074.1  interleukin-18 receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YLY8, B8PQ41
    Conserved Domains (3) summary
    PHA02785
    Location:24 → 306
    PHA02785; IL-beta-binding protein; Provisional
    smart00255
    Location:381 → 530
    TIR; Toll - interleukin 1 - resistance
    cl11960
    Location:136 → 185
    Ig; Immunoglobulin domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    133968354..133986406
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046908066.1 → XP_046764022.1  interleukin-18 receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YLY8, B8PQ41

  2. XM_046908067.1 → XP_046764023.1  interleukin-18 receptor 1 isoform X2

    UniProtKB/TrEMBL
    B8PQ41

  3. XM_046908065.1 → XP_046764021.1  interleukin-18 receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YLY8, B8PQ41
Nucleotide Protein
Heading Accession and Version

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