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Caf1-55 Chromatin assembly factor 1, p55 subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41836, updated on 9-Nov-2019

Summary

Official Symbol
Caf1-55provided by FlyBase
Official Full Name
Chromatin assembly factor 1, p55 subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0263979
Locus tag
Dmel_CG4236
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
154659_at; 55; caf-1; Caf-1; CAF-1; caf1; Caf1; CAF1; Caf1 (p55); caf1 p55; CAF1-55; CAF1-p55; Caf1/p55; Caf1p55; CAF1p55; CG4236; d-CAF1; dCAF-1; dCAF-1 p55; dCAF-1-p55; dCAF1; dCAF1-p55; Dmel\CG4236; dNURF; MSI1/RbAp48/CAC3/LIN-53; Nurf; NURF; Nurf 55; NURF 55; Nurf-55; NURF-55; nurf55; Nurf55; NURF55; p55; P55; p55 CAF1; p55/NURF-55; p55CAF1; RbAp46/48; RbAp48; RBAP48; S(ls)3

Genomic context

See Caf1-55 in Genome Data Viewer
Location:
88E3-88E3; 3-56 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15225576..15227564)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11051298..11053286)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Rpb7 Neighboring gene uncharacterized protein Neighboring gene Arginine methyltransferase 3 Neighboring gene mitochondrial ribosomal protein S10

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Caf1-55 gene: The Caf1-55 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
DNA repair TAS
Traceable Author Statement
more info
PubMed 
chromatin assembly IDA
Inferred from Direct Assay
more info
PubMed 
chromatin assembly ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
chromatin silencing IPI
Inferred from Physical Interaction
more info
PubMed 
eggshell chorion gene amplification IC
Inferred by Curator
more info
PubMed 
histone acetylation IDA
Inferred from Direct Assay
more info
PubMed 
histone lysine methylation IDA
Inferred from Direct Assay
more info
PubMed 
histone methylation IDA
Inferred from Direct Assay
more info
PubMed 
mitotic cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleosome assembly IDA
Inferred from Direct Assay
more info
PubMed 
nucleosome mobilization IDA
Inferred from Direct Assay
more info
PubMed 
nucleosome positioning IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of gene expression IGI
Inferred from Genetic Interaction
more info
PubMed 
NOT regulation of histone H3-K27 methylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
segment specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
NOT ACF complex IDA
Inferred from Direct Assay
more info
PubMed 
CAF-1 complex IDA
Inferred from Direct Assay
more info
PubMed 
ESC/E(Z) complex IDA
Inferred from Direct Assay
more info
PubMed 
Myb complex IDA
Inferred from Direct Assay
more info
PubMed 
NURF complex IDA
Inferred from Direct Assay
more info
PubMed 
NURF complex IPI
Inferred from Physical Interaction
more info
PubMed 
NURF complex TAS
Traceable Author Statement
more info
PubMed 
NuRD complex IDA
Inferred from Direct Assay
more info
PubMed 
Sin3-type complex IDA
Inferred from Direct Assay
more info
PubMed 
histone methyltransferase complex IDA
Inferred from Direct Assay
more info
PubMed 
histone methyltransferase complex IPI
Inferred from Physical Interaction
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
polytene chromosome IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor complex IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
chromatin assembly factor 1, p55 subunit
Names
CG4236-PA
CG4236-PB
Caf1-55-PA
Caf1-55-PB
Nurf55/CAF1
chromatin assembly Factor-1
chromatin assembly factor 1
chromatin assembly factor 1 subunit
chromatin associated factor-1 subunit
nucleosome remodeling factor
nucleosome remodeling factor - 55kD
p55

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    15225576..15227564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079630.4NP_524354.1  chromatin assembly factor 1, p55 subunit, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524354.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24572
    UniProtKB/TrEMBL
    C0MJE4
    Related
    FBpp0082511, FBtr0083052
    Conserved Domains (4) summary
    COG2319
    Location:118411
    WD40; WD40 repeat [General function prediction only]
    pfam12265
    Location:2391
    CAF1C_H4-bd; Histone-binding protein RBBP4 or subunit C of CAF1 complex
    sd00039
    Location:132179
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:127408
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. NM_001170146.2NP_001163617.1  chromatin assembly factor 1, p55 subunit, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163617.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JIL4
    Related
    FBpp0291059, FBtr0301845
    Conserved Domains (4) summary
    COG2319
    Location:117410
    WD40; WD40 repeat [General function prediction only]
    pfam12265
    Location:2290
    CAF1C_H4-bd; Histone-binding protein RBBP4 or subunit C of CAF1 complex
    sd00039
    Location:131178
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:126407
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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