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C1R complement C1r [ Gallus gallus (chicken) ]

Gene ID: 418295, updated on 13-Apr-2026
Official Symbol
C1Rprovided by CGNC
Official Full Name
complement C1rprovided by CGNC
Primary source
CGNC:50728
See related
Ensembl:ENSGALG00010023655
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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See C1R in Genome Data Viewer
Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (77340916..77348374, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (77541341..77548797, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene lysophosphatidylcholine acyltransferase 3 Neighboring gene complement C1s Neighboring gene calsyntenin 3 Neighboring gene retinol binding protein 5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
complement C1r subcomponent
Names
complement component 1, r subcomponent
XP_040517556.1
XP_416518.2

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    77340916..77348374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_416518.8 → XP_416518.2  complement C1r subcomponent

    UniProtKB/TrEMBL
    A0A8V0ZXB2, F1NAB7
    Related
    ENSGALP00010034995.1, ENSGALT00010057622.1
    Conserved Domains (6) summary
    smart00020
    Location:459 → 703
    Tryp_SPc; Trypsin-like serine protease
    smart00032
    Location:377 → 431
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    smart00042
    Location:29 → 140
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    pfam00084
    Location:310 → 372
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:194 → 303
    CUB; CUB domain
    pfam14670
    Location:162 → 190
    FXa_inhibition; Coagulation Factor Xa inhibitory site

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    77541341..77548797 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040661622.2 → XP_040517556.1  complement C1r subcomponent

    UniProtKB/TrEMBL
    A0A8V0ZXB2, F1NAB7
    Conserved Domains (6) summary
    smart00020
    Location:459 → 703
    Tryp_SPc; Trypsin-like serine protease
    smart00032
    Location:377 → 431
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    smart00042
    Location:29 → 140
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    pfam00084
    Location:310 → 372
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:194 → 303
    CUB; CUB domain
    pfam14670
    Location:162 → 190
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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