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A2M alpha-2-macroglobulin [ Gallus gallus (chicken) ]

Gene ID: 418251, updated on 8-Jul-2018
Official Symbol
A2Mprovided by CGNC
Official Full Name
alpha-2-macroglobulinprovided by CGNC
Primary source
CGNC:50716
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
See A2M in Genome Data Viewer
Location:
chromosome: 1
Exon count:
37
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 1 NC_006088.5 (75907286..75936143)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 1 NC_006088.4 (76229983..76255770)

Chromosome 1 - NC_006088.5Genomic Context describing neighboring genes Neighboring gene polyhomeotic homolog 1 Neighboring gene mannose-6-phosphate receptor, cation dependent Neighboring gene alpha-2-macroglobulin-like Neighboring gene platelet glycoprotein VI-like

Products Interactant Other Gene Complex Source Pubs Description

Homology

Preferred Names
alpha-2-macroglobulin-P; alpha-2-macroglobulin

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006088.5 Reference GRCg6a Primary Assembly

    Range
    75907286..75936143
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025142803.1XP_024998571.1  alpha-2-macroglobulin isoform X1

    Conserved Domains (6) summary
    cd02897
    Location:9661266
    A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
    pfam00207
    Location:746836
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:128220
    A2M_N; MG2 domain
    pfam07677
    Location:13781423
    A2M_recep; A-macroglobulin receptor
    pfam07703
    Location:458604
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region
    cl23771
    Location:341412
    Big_3_5; Bacterial Ig-like domain (group 3)
  2. XM_025142810.1XP_024998578.1  alpha-2-macroglobulin isoform X2

    Conserved Domains (6) summary
    cd02897
    Location:9661266
    A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
    pfam00207
    Location:746836
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:128220
    A2M_N; MG2 domain
    pfam07677
    Location:13781465
    A2M_recep; A-macroglobulin receptor
    pfam07703
    Location:458604
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region
    cl23771
    Location:341412
    Big_3_5; Bacterial Ig-like domain (group 3)
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