U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SCUBE1 signal peptide, CUB domain and EGF like domain containing 1 [ Gallus gallus (chicken) ]

Gene ID: 418228, updated on 5-Aug-2026
Symbol
SCUBE1provided by CGNC
Full Name
signal peptide, CUB domain and EGF like domain containing 1provided by CGNC
Primary source
CGNC:10569
See related
Ensembl:ENSGALG00010011981
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See SCUBE1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
23
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (68640413..68847684, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (68940975..69147791, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene malonyl-CoA-acyl carrier protein transacylase Neighboring gene translocator protein Neighboring gene tubulin tyrosine ligase like 12 Neighboring gene uncharacterized LOC121109071 Neighboring gene metallophosphoesterase domain containing 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
signal peptide, CUB and EGF-like domain-containing protein 1
Names
signal peptide, CUB domain, EGF-like 1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    68640413..68847684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015291284.3 → XP_015146770.1  signal peptide, CUB and EGF-like domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8V0YFJ3
    Conserved Domains (5) summary
    smart00179
    Location:320 → 350
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:791 → 902
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:739 → 786
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:34 → 69
    EGF_3; EGF domain
    pfam14670
    Location:283 → 318
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_015291278.3 → XP_015146764.1  signal peptide, CUB and EGF-like domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YDB7, A0A8V0YFJ3
    Related
    ENSGALP00010016491.1, ENSGALT00010028683.1
    Conserved Domains (5) summary
    smart00179
    Location:320 → 350
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:798 → 909
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:746 → 793
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:34 → 69
    EGF_3; EGF domain
    pfam14670
    Location:283 → 318
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_015291272.4 → XP_015146758.1  signal peptide, CUB and EGF-like domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y753
    Conserved Domains (5) summary
    smart00179
    Location:350 → 380
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:821 → 932
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:769 → 816
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:34 → 69
    EGF_3; EGF domain
    pfam14670
    Location:313 → 348
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  4. XM_015291268.4 → XP_015146754.1  signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y753, A0A8V0YFI3
    Related
    ENSGALP00010016487.1, ENSGALT00010028679.1
    Conserved Domains (5) summary
    smart00179
    Location:350 → 380
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:828 → 939
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:776 → 823
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:34 → 69
    EGF_3; EGF domain
    pfam14670
    Location:313 → 348
    FXa_inhibition; Coagulation Factor Xa inhibitory site

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    68940975..69147791 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040658000.1 → XP_040513934.1  signal peptide, CUB and EGF-like domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8V0YFJ3
    Conserved Domains (5) summary
    smart00179
    Location:320 → 350
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:791 → 902
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:739 → 786
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:34 → 69
    EGF_3; EGF domain
    pfam14670
    Location:283 → 318
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_040657999.1 → XP_040513933.1  signal peptide, CUB and EGF-like domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YDB7, A0A8V0YFJ3
    Conserved Domains (5) summary
    smart00179
    Location:320 → 350
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:798 → 909
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:746 → 793
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:34 → 69
    EGF_3; EGF domain
    pfam14670
    Location:283 → 318
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_040657998.2 → XP_040513932.1  signal peptide, CUB and EGF-like domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y753
    Conserved Domains (5) summary
    smart00179
    Location:350 → 380
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:821 → 932
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:769 → 816
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:34 → 69
    EGF_3; EGF domain
    pfam14670
    Location:313 → 348
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  4. XM_040658001.2 → XP_040513935.1  signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y753, A0A8V0YFI3
    Conserved Domains (5) summary
    smart00179
    Location:350 → 380
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:828 → 939
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:776 → 823
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:34 → 69
    EGF_3; EGF domain
    pfam14670
    Location:313 → 348
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.