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prrF2 [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 4179185, updated on 24-Sep-2023

Summary

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Gene symbol
prrF2
Locus tag
PA4704.2
Gene type
ncRNA
RNA name
other
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (5284172..5284319)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene cAMP-binding protein A Neighboring gene Neighboring gene hypothetical protein Neighboring gene hemin importer ATP-binding subunit Neighboring gene ABC transporter permease

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Pseudomonas aeruginosa PrrF1 and PrrF2 Small Regulatory RNAs Promote 2-Alkyl-4-Quinolone Production through Redundant Regulation of the antR mRNA. Djapgne L, et al. J Bacteriol, 2018 May 15. PMID 29507088, Free PMC Article
  2. The Pseudomonas aeruginosa PrrF Small RNAs Regulate Iron Homeostasis during Acute Murine Lung Infection. Reinhart AA, et al. Infect Immun, 2017 May. PMID 28289146, Free PMC Article
  3. The Pseudomonas aeruginosa CrcZ RNA interferes with Hfq-mediated riboregulation. Sonnleitner E, et al. PLoS One, 2017. PMID 28686727, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These studies provide a mechanistic description of how the PrrF1 and PrrF2 sRNAs mediate virulence traits, such as 2-akyl-4(1H)-quinolone metabolite production, in P. aeruginosa.
    Title: The Pseudomonas aeruginosa PrrF1 and PrrF2 Small Regulatory RNAs Promote 2-Alkyl-4-Quinolone Production through Redundant Regulation of the antR mRNA.
  2. The studies further revealed that the Hfq-titrating RNA CrcZ can interfere with PrrF1-2/Hfq-mediated regulation of antR during the translation process.
    Title: The Pseudomonas aeruginosa CrcZ RNA interferes with Hfq-mediated riboregulation.
  3. These analyses indicate that the PrrF1 and PrrF2 small RNAs, but not PrrH, are required for acute lung infection by Pseudomonas aeruginosa.
    Title: The Pseudomonas aeruginosa PrrF Small RNAs Regulate Iron Homeostasis during Acute Murine Lung Infection.
Submit: New GeneRIF Correction

General gene information

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protein_bind

  • Loc: 5284179-5284197 bound_moiety = Fur , experiment = "EMSA [PMID: 15210934, 8633080]" , experiment = DNAse footprinting [PMID: 8633080] , experiment = Genomic SELEX [PMID: 8633080] , experiment = Northern blot [PMID: 15210934]

Gene Ontology Provided by PseudoCAP

Process Evidence Code Pubs
acts_upstream_of_or_within anthranilate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cellular response to iron ion starvation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of carbon utilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of cellular response to iron ion starvation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within sRNA-mediated post-transcriptional gene silencing IMP
Inferred from Mutant Phenotype
more info
 PubMed 

Gene LinkOut

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Molecular Biology Databases