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FGD6 FYVE, RhoGEF and PH domain containing 6 [ Gallus gallus (chicken) ]

Gene ID: 417908, updated on 13-Apr-2026
Symbol
FGD6provided by CGNC
Full Name
FYVE, RhoGEF and PH domain containing 6provided by CGNC
Primary source
CGNC:50618
See related
Ensembl:ENSGALG00010011738
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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Try the new Transcripts and proteins table
See FGD6 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
21
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (45422799..45490682, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (45774339..45842223, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase subunit A12 Neighboring gene nuclear receptor subfamily 2, group C, member 1 Neighboring gene vezatin, adherens junctions transmembrane protein Neighboring gene uncharacterized LOC112533391 Neighboring gene uncharacterized LOC101751743 Neighboring gene uncharacterized LOC121109142

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
FYVE, RhoGEF and PH domain-containing protein 6

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    45422799..45490682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015283990.4 → XP_015139476.2  FYVE, RhoGEF and PH domain-containing protein 6

    UniProtKB/TrEMBL
    A0A8V0YCC0, A0A8V0YEJ5
    Related
    ENSGALP00010016113.1, ENSGALT00010028087.1
    Conserved Domains (4) summary
    smart00325
    Location:878 → 1062
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd13237
    Location:1339 → 1427
    PH2_FGD5_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 5 and 6 pleckstrin homology (PH) domain, C-terminus
    cd15793
    Location:1080 → 1202
    PH1_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia protein 6, N-terminal Pleckstrin Homology (PH) domain
    cd15743
    Location:1220 → 1280
    FYVE_FGD6; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein 6 (FGD6) and similar proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    45774339..45842223 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040659038.2 → XP_040514972.1  FYVE, RhoGEF and PH domain-containing protein 6

    UniProtKB/TrEMBL
    A0A8V0YCC0, A0A8V0YEJ5
    Conserved Domains (4) summary
    smart00325
    Location:878 → 1062
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd13237
    Location:1339 → 1427
    PH2_FGD5_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 5 and 6 pleckstrin homology (PH) domain, C-terminus
    cd15793
    Location:1080 → 1202
    PH1_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia protein 6, N-terminal Pleckstrin Homology (PH) domain
    cd15743
    Location:1220 → 1280
    FYVE_FGD6; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein 6 (FGD6) and similar proteins
Nucleotide Protein
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