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kibra [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41783, updated on 26-Aug-2021

Summary

Official Symbol
kibraprovided by FlyBase
Primary source
FLYBASE:FBgn0262127
Locus tag
Dmel_CG33967
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12600; CG33967; CG7552; Dmel\CG33967; DmKibra; kbr; Kbr; kib; Kib; Kibra; l(3)02404; l(3)j5C3; l(3)neo42; ORE-2; RE26350
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Genomic context

See kibra in Genome Data Viewer
Location:
88D1-88D2; 3-56 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14697689..14724261, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10523411..10549983, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene meltrin Neighboring gene Histone H1 variant BigH1 Neighboring gene uncharacterized protein Neighboring gene effete

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

mobile_element

  • Loc: c14707050-14706982 mobile_element_type = transposon:INE-1{}4043

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables molecular adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of Kibra-Ex-Mer complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of Kibra-Ex-Mer complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in apicomedial cortex IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasmic side of apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
kibra
Names
CG33967-PA
CG33967-PB
kibra ortholog
kibra-PA
kibra-PB
lethal (3) neo42

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    14697689..14724261 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300400.1NP_001287329.1  kibra, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287329.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VFG8
    UniProtKB/TrEMBL
    A0A0B4LH59
    Related
    FBpp0310756, FBtr0344383
    Conserved Domains (3) summary
    cd08680
    Location:693813
    C2_Kibra; C2 domain found in Human protein Kibra
    cd00201
    Location:5787
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam00397
    Location:103132
    WW; WW domain
  2. NM_001038966.2NP_001034055.1  kibra, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001034055.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VFG8
    UniProtKB/TrEMBL
    A0A0B4LH59
    Related
    FBpp0099467, FBtr0100008
    Conserved Domains (3) summary
    cd08680
    Location:693813
    C2_Kibra; C2 domain found in Human protein Kibra
    cd00201
    Location:5787
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam00397
    Location:103132
    WW; WW domain
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