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NELL2 neural EGFL like 2 [ Gallus gallus (chicken) ]

Gene ID: 417799, updated on 13-Apr-2026
Official Symbol
NELL2provided by CGNC
Official Full Name
neural EGFL like 2provided by CGNC
Primary source
CGNC:7309
See related
Ensembl:ENSGALG00010013749
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
nel
Orthologs
all
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Try the new Transcripts and proteins table
See NELL2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
20
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (30482012..30625498, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (30819888..30963097, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121106857 Neighboring gene uncharacterized LOC121106859 Neighboring gene arrestin domain containing 5 Neighboring gene prolactin 2 Neighboring gene developing brain homeobox 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. NELL2 promotes motor and sensory neuron differentiation and stimulates mitogenesis in DRG in vivo. Nelson BR, et al. Dev Biol, 2004 Jun 15. PMID 15183717
  2. New gene, nel, encoding a M(r) 93 K protein with EGF-like repeats is strongly expressed in neural tissues of early stage chick embryos. Matsuhashi S, et al. Dev Dyn, 1995 Jun. PMID 7655083
  3. Structure-function analysis of Nel, a thrombospondin-1-like glycoprotein involved in neural development and functions. Nakamura R, et al. J Biol Chem, 2012 Jan 27. PMID 22157752, Free PMC Article
  4. Qualitative and quantitative peptidomic and proteomic approaches to phenotyping chicken semen. Labas V, et al. J Proteomics, 2015 Jan 1. PMID 25086240
  5. Merging extracellular domains: fold prediction for laminin G-like and amino-terminal thrombospondin-like modules based on homology to pentraxins. Beckmann G, et al. J Mol Biol, 1998 Feb 6. PMID 9480764

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
protein NEL
Names
93 kDa protein
Mr 93 K protein

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030740.2 → NP_001025911.1  protein NEL precursor

    See identical proteins and their annotated locations for NP_001025911.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000012
    UniProtKB/Swiss-Prot
    Q90827
    UniProtKB/TrEMBL
    A0A8V0YNG1
    Related
    ENSGALP00010019514.1, ENSGALT00010033009.1
    Conserved Domains (6) summary
    smart00179
    Location:555 → 589
    EGF_CA; Calcium-binding EGF-like domain
    smart00210
    Location:29 → 214
    TSPN; Thrombospondin N-terminal -like domains
    pfam07645
    Location:602 → 633
    EGF_CA; Calcium-binding EGF domain
    pfam12947
    Location:486 → 521
    EGF_3; EGF domain
    cl00057
    Location:435 → 477
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl17735
    Location:274 → 330
    VWC; von Willebrand factor type C domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    30482012..30625498 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    30819888..30963097 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q90827.1 GenPept UniProtKB/Swiss-Prot:Q90827

Gene LinkOut

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Molecular Biology Databases
Research Materials