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GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 [ Gallus gallus (chicken) ]

Gene ID: 417584, updated on 5-Aug-2026
Official Symbol
GIT1provided by CGNC
Official Full Name
G protein-coupled receptor kinase interacting ArfGAP 1provided by CGNC
Primary source
CGNC:50555
See related
Ensembl:ENSGALG00010029697
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
p95-APP1
Orthologs
all
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See GIT1 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
22
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 19 NC_052550.1 (6546911..6554819, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 19 NC_052591.1 (6283925..6291827, complement)

Chromosome 19 - NC_052550.1Genomic Context describing neighboring genes Neighboring gene crystallin beta A1 Neighboring gene NUFIP2, FMR1 interacting protein 2 Neighboring gene TAO kinase 1 Neighboring gene microRNA mir-12235 Neighboring gene ankyrin repeat domain 13B Neighboring gene coronin 6

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Characterization of the endogenous GIT1-betaPIX complex, and identification of its association to membranes. Botrugno OA, et al. Eur J Cell Biol, 2006 Jan. PMID 16373173
  2. p95-APP1 links membrane transport to Rac-mediated reorganization of actin. Di Cesare A, et al. Nat Cell Biol, 2000 Aug. PMID 10934473
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in brain development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of ARF protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
ARF GTPase-activating protein GIT1
Names
ArfGAP-putative, Pix-interacting, paxillin-interacting protein 1
G protein-coupled receptor kinase-interactor 1
NP_989627.2
XP_015151254.2
XP_015151255.2
XP_015151256.2
XP_046786067.1
XP_046786068.1
XP_046786069.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204296.2 → NP_989627.2  ARF GTPase-activating protein GIT1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000323
    UniProtKB/TrEMBL
    A0A8V1AER5, A0A8V1AK39
    Related
    ENSGALP00010044522.1, ENSGALT00010071832.1
    Conserved Domains (6) summary
    smart00555
    Location:328 → 358
    GIT; Helical motif in the GIT family of ADP-ribosylation factor GTPase-activating proteins
    smart00338
    Location:435 → 468
    BRLZ; basic region leucin zipper
    COG0666
    Location:37 → 243
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:137 → 165
    ANK; ANK repeat [structural motif]
    cd08846
    Location:1 → 111
    ArfGap_GIT1; GIT1 GTPase activating protein for Arf
    cl23881
    Location:272 → 294
    GIT_SHD; Spa2 homology domain (SHD) of GIT

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052550.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    6546911..6554819 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015295768.4 → XP_015151254.2  ARF GTPase-activating protein GIT1 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AK39
    Related
    ENSGALP00010044519.1, ENSGALT00010071829.1
    Conserved Domains (6) summary
    smart00555
    Location:328 → 358
    GIT; Helical motif in the GIT family of ADP-ribosylation factor GTPase-activating proteins
    smart00338
    Location:435 → 468
    BRLZ; basic region leucin zipper
    COG0666
    Location:37 → 243
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:137 → 165
    ANK; ANK repeat [structural motif]
    cd08846
    Location:1 → 111
    ArfGap_GIT1; GIT1 GTPase activating protein for Arf
    cl23881
    Location:272 → 294
    GIT_SHD; Spa2 homology domain (SHD) of GIT

  2. XM_015295769.4 → XP_015151255.2  ARF GTPase-activating protein GIT1 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AK39
    Conserved Domains (6) summary
    smart00555
    Location:337 → 367
    GIT; Helical motif in the GIT family of ADP-ribosylation factor GTPase-activating proteins
    smart00338
    Location:444 → 477
    BRLZ; basic region leucin zipper
    COG0666
    Location:37 → 243
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:137 → 165
    ANK; ANK repeat [structural motif]
    cl28907
    Location:1 → 111
    ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
    cl23881
    Location:281 → 303
    GIT_SHD; Spa2 homology domain (SHD) of GIT

  3. XM_015295770.4 → XP_015151256.2  ARF GTPase-activating protein GIT1 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AK39, A0A8V1ANE2
    Related
    ENSGALP00010044520.1, ENSGALT00010071830.1
    Conserved Domains (6) summary
    smart00555
    Location:337 → 367
    GIT; Helical motif in the GIT family of ADP-ribosylation factor GTPase-activating proteins
    smart00338
    Location:444 → 477
    BRLZ; basic region leucin zipper
    COG0666
    Location:37 → 243
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:137 → 165
    ANK; ANK repeat [structural motif]
    cd08846
    Location:1 → 111
    ArfGap_GIT1; GIT1 GTPase activating protein for Arf
    cl23881
    Location:281 → 303
    GIT_SHD; Spa2 homology domain (SHD) of GIT

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052591.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    6283925..6291827 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046930112.1 → XP_046786068.1  ARF GTPase-activating protein GIT1 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AK39

  2. XM_046930113.1 → XP_046786069.1  ARF GTPase-activating protein GIT1 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AK39

  3. XM_046930111.1 → XP_046786067.1  ARF GTPase-activating protein GIT1 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AK39
Nucleotide Protein Strain
Heading Accession and Version

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