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YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon [ Gallus gallus (chicken) ]

Gene ID: 417554, updated on 12-Aug-2018

Summary

Symbol
YWHAEprovided by CGNC
Full Name
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilonprovided by CGNC
Primary source
CGNC:50550
See related
Ensembl:ENSGALG00000002661
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs

Genomic context

See YWHAE in Genome Data Viewer
Location:
chromosome: 19
Exon count:
7
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 19 NC_006106.5 (5331007..5350911)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 19 NC_006106.4 (5167629..5187560)

Chromosome 19 - NC_006106.5Genomic Context describing neighboring genes Neighboring gene nuclear cap binding subunit 3 Neighboring gene uncharacterized LOC107054795 Neighboring gene CRK proto-oncogene, adaptor protein Neighboring gene myosin IC Neighboring gene inositol polyphosphate-5-phosphatase K

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Calcium Regulation in the Cardiac Cell, organism-specific biosystem (from WikiPathways)
    Calcium Regulation in the Cardiac Cell, organism-specific biosystemCalcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins. Calcium can act in signal transduction after influx resu...
  • Cell cycle, organism-specific biosystem (from KEGG)
    Cell cycle, organism-specific biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
  • Cell cycle, conserved biosystem (from KEGG)
    Cell cycle, conserved biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
  • Oocyte meiosis, organism-specific biosystem (from KEGG)
    Oocyte meiosis, organism-specific biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segrega...
  • Oocyte meiosis, conserved biosystem (from KEGG)
    Oocyte meiosis, conserved biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segrega...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 
histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 
identical protein binding IEA
Inferred from Electronic Annotation
more info
 
ion channel binding IEA
Inferred from Electronic Annotation
more info
 
phosphoserine residue binding IEA
Inferred from Electronic Annotation
more info
 
potassium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 
protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
scaffold protein binding IEA
Inferred from Electronic Annotation
more info
 
ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
MAPK cascade ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to heat ISS
Inferred from Sequence or Structural Similarity
more info
 
cerebral cortex development IEA
Inferred from Electronic Annotation
more info
 
hippocampus development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of calcium ion export across plasma membrane IEA
Inferred from Electronic Annotation
more info
 
negative regulation of calcium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
negative regulation of peptidyl-serine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
neuron migration IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein export from nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
protein localization to nucleus IEA
Inferred from Electronic Annotation
more info
 
protein targeting IEA
Inferred from Electronic Annotation
more info
 
regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 
regulation of membrane repolarization IEA
Inferred from Electronic Annotation
more info
 
regulation of potassium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
14-3-3 protein epsilon
Names
14-3-3E
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006219.1NP_001006219.1  14-3-3 protein epsilon

    See identical proteins and their annotated locations for NP_001006219.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ719304
    UniProtKB/Swiss-Prot
    Q5ZMT0
    UniProtKB/TrEMBL
    F1P2P9
    Related
    ENSGALP00000039133.2, ENSGALT00000039926.3
    Conserved Domains (1) summary
    cd10020
    Location:4233
    14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006106.5 Reference GRCg6a Primary Assembly

    Range
    5331007..5350911
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015295739.2XP_015151225.1  14-3-3 protein epsilon isoform X1

    Conserved Domains (1) summary
    cd10020
    Location:4233
    14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein
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