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MYL2 myosin, light chain 2, regulatory, cardiac, slow [ Gallus gallus (chicken) ]

Gene ID: 416874, updated on 15-Feb-2025
Official Symbol
MYL2provided by CGNC
Official Full Name
myosin, light chain 2, regulatory, cardiac, slowprovided by CGNC
Primary source
CGNC:50364
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
G2; MLC2; MLC-2A
Orthologs
human mouse all
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See MYL2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
7
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (6049150..6053161, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (6059855..6063865, complement)

Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1 catalytic subunit gamma Neighboring gene coiled-coil domain containing 63 Neighboring gene cut like homeobox 2 Neighboring gene family with sequence similarity 109 member A

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The nucleotide sequence of myosin light chain (L-2A) mRNA from embryonic chicken cardiac muscle tissue. Arnold HH, et al. Nucleic Acids Res, 1983 Feb 25. PMID 6298733, Free PMC Article
  2. Characterization of 5'-flanking region of heart myosin light chain 2A gene. Structural and functional evidence for promoter activity. Zarraga AM, et al. J Biol Chem, 1986 Oct 15. PMID 3020054
  3. Isolation and characterization of the chicken cardiac myosin light chain (L-2A) gene. Evidence for two additional N-terminal amino acids. Winter B, et al. J Biol Chem, 1985 Apr 10. PMID 2984206
  4. Amino acid sequences of the cardiac L-2A, L-2B and gizzard 17 000-Mr light chains of chicken muscle myosin. Matsuda G, et al. FEBS Lett, 1981 Dec 7. PMID 7319048
  5. Conserved BK channel-protein interactions reveal signals relevant to cell death and survival. Sokolowski B, et al. PLoS One, 2011. PMID 22174833, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cardiac muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in muscle cell fate specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in myofibril IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
myosin regulatory light chain 2A, cardiac muscle isoform
Names
light polypeptide 2
myosin light chain 2
myosin, light polypeptide 2, regulatory, cardiac, slow

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271929.1 → NP_001258858.1  myosin regulatory light chain 2A, cardiac muscle isoform

    See identical proteins and their annotated locations for NP_001258858.1

    Status: VALIDATED

    Source sequence(s)
    BU257651, JAENSK010000260
    UniProtKB/Swiss-Prot
    P02610
    Conserved Domains (1) summary
    COG5126
    Location:15 → 162
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    6049150..6053161 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    6059855..6063865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P02610.2 GenPept UniProtKB/Swiss-Prot:P02610

Gene LinkOut

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Molecular Biology Databases
Research Materials