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SPINK7 serine peptidase inhibitor, Kazal type 7 (putative) [ Gallus gallus (chicken) ]

Gene ID: 416236, updated on 24-Sep-2021

Summary

Official Symbol
SPINK7provided by CGNC
Official Full Name
serine peptidase inhibitor, Kazal type 7 (putative)provided by CGNC
Primary source
CGNC:50205
See related
Ensembl:ENSGALG00000003512
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
OM; OVM; SPIK7
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Genomic context

See SPINK7 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
10
Annotation release Status Assembly Chr Location
105 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (10178673..10184657)
105 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.1) 13 NC_052585.1 (10181459..10186934)
104 previous assembly GRCg6a (GCF_000002315.5) 13 NC_006100.5 (11280307..11286011)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 13 NC_006100.4 (10574064..10579774)

Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene serine protease inhibitor Kazal-type 5-like Neighboring gene serine peptidase inhibitor, Kazal type 5 Neighboring gene ovoinhibitor-like Neighboring gene serine protease inhibitor Kazal-type 6-like

Genomic regions, transcripts, and products

Bibliography

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables IgE binding IDA
Inferred from Direct Assay
more info
PubMed 
enables IgE binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables IgG binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables carbohydrate binding IDA
Inferred from Direct Assay
more info
PubMed 
enables serine-type endopeptidase inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
involved_in response to steroid hormone TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular space NAS
Non-traceable Author Statement
more info
PubMed 
located_in extracellular space TAS
Traceable Author Statement
more info
PubMed 
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ovomucoid
Names
allergen Gal d 1
allergen Gal d I

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001112662.2NP_001106132.1  ovomucoid isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the coding region, compared to variant 1, and encodes a shorter isoform (2), compared to isoform 1.
    Source sequence(s)
    JAENSK010000256
    Conserved Domains (2) summary
    cd01327
    Location:4286
    KAZAL_PSTI; Kazal-type pancreatic secretory trypsin inhibitors (PSTI) and related proteins, including the second domain of the ovomucoid turkey inhibitor and the C-terminal domain of the esophagus cancer-related gene-2 protein (ECRG-2), are members of the ...
    pfam00050
    Location:108151
    Kazal_1; Kazal-type serine protease inhibitor domain
  2. NM_001308494.2NP_001295423.1  ovomucoid isoform 1 precursor

    See identical proteins and their annotated locations for NP_001295423.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    JAENSK010000256
    UniProtKB/Swiss-Prot
    P01005
    Related
    ENSGALP00000005544.2, ENSGALT00000005554.5
    Conserved Domains (2) summary
    cd01327
    Location:4286
    KAZAL_PSTI; Kazal-type pancreatic secretory trypsin inhibitors (PSTI) and related proteins, including the second domain of the ovomucoid turkey inhibitor and the C-terminal domain of the esophagus cancer-related gene-2 protein (ECRG-2), are members of the ...
    pfam00050
    Location:108151
    Kazal_1; Kazal-type serine protease inhibitor domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    10178673..10184657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040646894.1XP_040502828.1  ovomucoid isoform X1

    Conserved Domains (2) summary
    cd01327
    Location:4286
    KAZAL_PSTI; Kazal-type pancreatic secretory trypsin inhibitors (PSTI) and related proteins, including the second domain of the ovomucoid turkey inhibitor and the C-terminal domain of the esophagus cancer-related gene-2 protein (ECRG-2), are members of the ...
    pfam00050
    Location:108151
    Kazal_1; Kazal-type serine protease inhibitor domain
  2. XM_015293764.3XP_015149250.1  ovomucoid isoform X2

    Conserved Domains (2) summary
    cd01327
    Location:4286
    KAZAL_PSTI; Kazal-type pancreatic secretory trypsin inhibitors (PSTI) and related proteins, including the second domain of the ovomucoid turkey inhibitor and the C-terminal domain of the esophagus cancer-related gene-2 protein (ECRG-2), are members of the ...
    pfam00050
    Location:108151
    Kazal_1; Kazal-type serine protease inhibitor domain
  3. XM_015293763.3XP_015149249.1  ovomucoid isoform X1

    UniProtKB/Swiss-Prot
    P01005
    Conserved Domains (2) summary
    cd01327
    Location:4286
    KAZAL_PSTI; Kazal-type pancreatic secretory trypsin inhibitors (PSTI) and related proteins, including the second domain of the ovomucoid turkey inhibitor and the C-terminal domain of the esophagus cancer-related gene-2 protein (ECRG-2), are members of the ...
    pfam00050
    Location:108151
    Kazal_1; Kazal-type serine protease inhibitor domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    10181459..10186934
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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