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BHLHE40 basic helix-loop-helix family member e40 [ Gallus gallus (chicken) ]

Gene ID: 416108, updated on 14-Feb-2019

Summary

Symbol
BHLHE40provided by CGNC
Full Name
basic helix-loop-helix family member e40provided by CGNC
Primary source
CGNC:6296
See related
Ensembl:ENSGALG00000008308
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
BHLHB2
Summary
This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]
Orthologs

Genomic context

See BHLHE40 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
5
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 12 NC_006099.5 (18986975..18991321)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 12 NC_006099.4 (18624949..18629296)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 12 NC_006099.3 (18572157..18576504)

Chromosome 12 - NC_006099.5Genomic Context describing neighboring genes Neighboring gene inositol 1,4,5-trisphosphate receptor type 1 Neighboring gene uncharacterized LOC112533364 Neighboring gene uncharacterized LOC107054403 Neighboring gene uncharacterized LOC107054404

Genomic regions, transcripts, and products

General gene information

Homology

General protein information

Preferred Names
class E basic helix-loop-helix protein 40
Names
basic helix-loop-helix domain containing, class B, 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277144.2NP_001264073.1  class E basic helix-loop-helix protein 40

    Status: VALIDATED

    Source sequence(s)
    AADN05000356, DR424259
    UniProtKB/TrEMBL
    A0A1D5PVD7
    Related
    ENSGALP00000056903.1, ENSGALT00000073347.3
    Conserved Domains (2) summary
    smart00511
    Location:140183
    ORANGE; Orange domain
    cd00083
    Location:54112
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006099.5 Reference GRCg6a Primary Assembly

    Range
    18986975..18991321
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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