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MCM2 minichromosome maintenance complex component 2 [ Gallus gallus (chicken) ]

Gene ID: 416027, updated on 20-Jun-2018

Summary

Symbol
MCM2provided by CGNC
Full Name
minichromosome maintenance complex component 2provided by CGNC
Primary source
CGNC:4524
See related
Ensembl:ENSGALG00000006037
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs

Genomic context

See MCM2 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
17
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 12 NC_006099.5 (10137397..10150146, complement)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 12 NC_006099.4 (9749554..9762286, complement)

Chromosome 12 - NC_006099.5Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and BTB domain containing 1 Neighboring gene podocalyxin like 2 Neighboring gene transmembrane protein adipocyte associated 1 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 6

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Cell cycle, organism-specific biosystem (from KEGG)
    Cell cycle, organism-specific biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
  • Cell cycle, organism-specific biosystem (from WikiPathways)
    Cell cycle, organism-specific biosystem(From http://en.wikipedia.org/wiki/Cell_cycle) The cell cycle is the series of events that takes place in a cell leading to its division and duplication (replication). Regulation of the cell cycle in...
  • Cell cycle, conserved biosystem (from KEGG)
    Cell cycle, conserved biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
  • DNA Replication, organism-specific biosystem (from WikiPathways)
    DNA Replication, organism-specific biosystemDNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "replication" in that each strand of the original ...
  • DNA replication, organism-specific biosystem (from KEGG)
    DNA replication, organism-specific biosystemA complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (D...
  • DNA replication, conserved biosystem (from KEGG)
    DNA replication, conserved biosystemA complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (D...
  • G1 to S cell cycle control, organism-specific biosystem (from WikiPathways)
    G1 to S cell cycle control, organism-specific biosystemIn the G1 phase there are two types of DNA damage responses, the p53-dependent and the p53-independent pathways. The p53-dependent responses inhibit CDKs through the up-regulation of genes encoding C...
  • MCM complex, organism-specific biosystem (from KEGG)
    MCM complex, organism-specific biosystemStructural complex; Genetic information processing; Replication system
  • MCM complex, conserved biosystem (from KEGG)
    MCM complex, conserved biosystemStructural complex; Genetic information processing; Replication system

General gene information

Homology

General protein information

Preferred Names
DNA replication licensing factor MCM2
Names
MCM2 minichromosome maintenance deficient 2, mitotin
NP_001006139.1
XP_015148569.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006139.1NP_001006139.1  DNA replication licensing factor MCM2

    See identical proteins and their annotated locations for NP_001006139.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ719593
    UniProtKB/TrEMBL
    Q5ZLZ1
    Related
    ENSGALP00000009709.4, ENSGALT00000009723.4
    Conserved Domains (4) summary
    smart00350
    Location:278787
    MCM; minichromosome maintenance proteins
    pfam12619
    Location:64169
    MCM2_N; Mini-chromosome maintenance protein 2
    pfam14551
    Location:185297
    MCM_N; MCM N-terminal domain
    cl21455
    Location:472646
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006099.5 Reference GRCg6a Primary Assembly

    Range
    10137397..10150146 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015293083.2XP_015148569.1  DNA replication licensing factor MCM2 isoform X1

    UniProtKB/TrEMBL
    F1NB20
    Conserved Domains (4) summary
    smart00350
    Location:319828
    MCM; minichromosome maintenance proteins
    pfam12619
    Location:105210
    MCM2_N; Mini-chromosome maintenance protein 2
    pfam14551
    Location:226338
    MCM_N; MCM N-terminal domain
    cl21455
    Location:513687
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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