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YTHDC2 YTH domain containing 2 [ Gallus gallus (chicken) ]

Gene ID: 415602, updated on 30-May-2026
Symbol
YTHDC2provided by CGNC
Full Name
YTH domain containing 2provided by CGNC
Primary source
CGNC:106
See related
Ensembl:ENSGALG00010008243
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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Try the new Transcripts and proteins table
See YTHDC2 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
29
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (46370811..46409153, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (46370811..46409153, complement)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene isochorismatase domain containing 1 Neighboring gene solute carrier family 27 (fatty acid transporter), member 6 Neighboring gene U2 spliceosomal RNA Neighboring gene mutated in colorectal cancers Neighboring gene decapping mRNA 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in intracellular anatomical structure IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
3'-5' RNA helicase YTHDC2
XP_004949328.1
XP_025000689.1
XP_046791805.1
XP_046791806.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    46370811..46409153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004949271.5 → XP_004949328.1  3'-5' RNA helicase YTHDC2 isoform X1

    Conserved Domains (9) summary
    cd06007
    Location:57 → 115
    R3H_DEXH_helicase; R3H domain of a group of proteins which also contain a DEXH-box helicase domain, and may function as ATP-dependent DNA or RNA helicases. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine ...
    smart00847
    Location:827 → 912
    HA2; Helicase associated domain (HA2) Add an annotation
    cd00046
    Location:221 → 360
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00204
    Location:498 → 583
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00271
    Location:621 → 753
    Helicase_C; Helicase conserved C-terminal domain
    pfam04146
    Location:1296 → 1411
    YTH; YT521-B-like domain
    pfam07717
    Location:950 → 1077
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
    pfam13637
    Location:520 → 570
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:516 → 548
    ANK; ANK repeat [structural motif]

  2. XM_025144921.3 → XP_025000689.1  3'-5' RNA helicase YTHDC2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y1J8
    Related
    ENSGALP00010011264.1, ENSGALT00010019716.1
    Conserved Domains (4) summary
    cd06007
    Location:57 → 115
    R3H_DEXH_helicase; R3H domain of a group of proteins which also contain a DEXH-box helicase domain, and may function as ATP-dependent DNA or RNA helicases. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine ...
    COG1643
    Location:200 → 1019
    HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
    sd00045
    Location:516 → 548
    ANK; ANK repeat [structural motif]
    pfam04146
    Location:1295 → 1426
    YTH; YT521-B-like domain

RNA

  1. XR_005842652.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    46370811..46409153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046935849.1 → XP_046791805.1  3'-5' RNA helicase YTHDC2 isoform X1

  2. XM_046935850.1 → XP_046791806.1  3'-5' RNA helicase YTHDC2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y1J8

RNA

  1. XR_006937577.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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