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hppD 4-hydroxyphenylpyruvate dioxygenase [ Streptomyces avermitilis MA-4680 = NBRC 14893 ]

Gene ID: 41542235, updated on 8-Apr-2026
Gene symbol
hppD
Gene description
4-hydroxyphenylpyruvate dioxygenase
Locus tag
SAVERM_RS26575
Gene type
protein coding
Organism
Streptomyces avermitilis MA-4680 = NBRC 14893 (strain: MA-4680, type-material: type strain of Streptomyces avermitilis)
Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Old locus tag
SAV_5149; SAVERM_5149
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Sequence:
NC_003155.5 (6253610..6254755)

NC_003155.5Genomic Context describing neighboring genes Neighboring gene betaine/proline/choline family ABC transporter ATP-binding protein Neighboring gene ABC transporter permease Neighboring gene Lrp/AsnC family transcriptional regulator Neighboring gene tetratricopeptide repeat protein Neighboring gene FAD-binding oxidoreductase

Genomic Sequence:
NC_003155.5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structure of the ferrous form of (4-hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis in complex with the therapeutic herbicide, NTBC. Brownlee JM, et al. Biochemistry, 2004 Jun 1. PMID 15157070
  2. A Streptomyces avermitilis gene encoding a 4-hydroxyphenylpyruvic acid dioxygenase-like protein that directs the production of homogentisic acid and an ochronotic pigment in Escherichia coli. Denoya CD, et al. J Bacteriol, 1994 Sep. PMID 8071207, Free PMC Article
  3. Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites. Omura S, et al. Proc Natl Acad Sci U S A, 2001 Oct 9. PMID 11572948, Free PMC Article
  4. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Ikeda H, et al. Nat Biotechnol, 2003 May. PMID 12692562

GeneRIFs: Gene References Into Functions

Preferred Names
4-hydroxyphenylpyruvate dioxygenase
WP_010986553.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003155.5 Reference assembly

    Range
    6253610..6254755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010986553.1 4-hydroxyphenylpyruvate dioxygenase

    See identical proteins and their annotated locations for WP_010986553.1

    UniProtKB/Swiss-Prot
    Q53586, Q93HN6
    UniProtKB/TrEMBL
    A0A4D4M1A7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q53586.2