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rela v-rel avian reticuloendotheliosis viral oncogene homolog A [ Danio rerio (zebrafish) ]

Gene ID: 415099, updated on 23-Sep-2018

Summary

Official Symbol
relaprovided by ZNC
Official Full Name
v-rel avian reticuloendotheliosis viral oncogene homolog Aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040825-4
See related
Ensembl:ENSDARG00000098696 Vega:OTTDARG00000040348
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
p65; nfkb3

Genomic context

See rela in Genome Data Viewer
Location:
chromosome: 7
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (767279..804593, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (630414..667803, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene DR1-associated protein 1 (negative cofactor 2 alpha) Neighboring gene zgc:63470 Neighboring gene uncharacterized LOC101883941 Neighboring gene si:cabz01076231.1 Neighboring gene cabz01076234.2 Neighboring gene uncharacterized LOC103911293

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
I-kappaB kinase/NF-kappaB signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NIK/NF-kappaB signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
anterior/posterior axis specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mesoderm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
positive regulation of apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
response to cytokine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
NF-kappaB complex IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transcription factor p65
Names
P65 transcription factor
v-rel reticuloendotheliosis viral oncogene homolog A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001839.2NP_001001839.2  transcription factor p65

    See identical proteins and their annotated locations for NP_001001839.2

    Status: VALIDATED

    Source sequence(s)
    CAAK05051228, CAAK05051229, CU896668
    UniProtKB/TrEMBL
    B3DHW2
    Related
    ENSDARP00000133181.3, ENSDART00000159359.3
    Conserved Domains (2) summary
    cd07885
    Location:18186
    RHD-n_RelA; N-terminal sub-domain of the Rel homology domain (RHD) of RelA
    cd01177
    Location:193289
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    767279..804593 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005170796.4XP_005170853.1  transcription factor p65 isoform X1

    UniProtKB/TrEMBL
    A0A0R4IQ31
    Related
    OTTDARP00000045344
    Conserved Domains (2) summary
    cd07885
    Location:18186
    RHD-n_RelA; N-terminal sub-domain of the Rel homology domain (RHD) of RelA
    cd01177
    Location:193289
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
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