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MPL MPL proto-oncogene, thrombopoietin receptor [ Gallus gallus (chicken) ]

Gene ID: 414804, updated on 3-Dec-2024
Symbol
MPLprovided by CGNC
Full Name
MPL proto-oncogene, thrombopoietin receptorprovided by CGNC
Primary source
CGNC:7572
See related
Ensembl:ENSGALG00010022689
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
c-mpl
Orthologs
human mouse all
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See MPL in Genome Data Viewer
Location:
chromosome: 8
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (19361455..19365614)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (19368622..19372781)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene chromosome 1 open reading frame 210 Neighboring gene tyrosine kinase with immunoglobulin like and EGF like domains 1 Neighboring gene cell division cycle 20 Neighboring gene ELOVL fatty acid elongase 1 Neighboring gene mediator complex subunit 8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemopoiesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
thrombopoietin receptor
Names
myeloproliferative leukemia virus oncogene

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001782.2 → NP_001001782.2  thrombopoietin receptor precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000239
    UniProtKB/TrEMBL
    A0A8V0ZPI6, Q6IYE8
    Related
    ENSGALP00010033395.1, ENSGALT00010055196.1
    Conserved Domains (1) summary
    cd00063
    Location:375 → 466
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    19361455..19365614
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040704534.2 → XP_040560468.1  thrombopoietin receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZRD4, Q6IYE8
    Related
    ENSGALP00010033392.1, ENSGALT00010055192.1
    Conserved Domains (1) summary
    cd00063
    Location:378 → 469
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  2. XM_046944333.1 → XP_046800289.1  thrombopoietin receptor isoform X2

    UniProtKB/TrEMBL
    Q6IYE8

  3. XM_040704531.2 → XP_040560465.1  thrombopoietin receptor isoform X3

    UniProtKB/TrEMBL
    Q6IYE8
    Conserved Domains (1) summary
    cd00063
    Location:397 → 510
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  4. XM_040704532.2 → XP_040560466.1  thrombopoietin receptor isoform X4

    UniProtKB/TrEMBL
    Q6IYE8
    Conserved Domains (1) summary
    cd00063
    Location:397 → 510
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  5. XM_040704533.2 → XP_040560467.1  thrombopoietin receptor isoform X6

    Conserved Domains (1) summary
    cd00063
    Location:397 → 510
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  6. XM_046944330.1 → XP_046800286.1  thrombopoietin receptor isoform X5

    UniProtKB/TrEMBL
    Q6IYE8

  7. XM_046944331.1 → XP_046800287.1  thrombopoietin receptor isoform X7

    UniProtKB/TrEMBL
    Q6IYE8

  8. XM_046944332.1 → XP_046800288.1  thrombopoietin receptor isoform X8

    UniProtKB/TrEMBL
    Q6IYE8

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    19368622..19372781
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046922455.1 → XP_046778411.1  thrombopoietin receptor isoform X1

    UniProtKB/TrEMBL
    Q6IYE8

  2. XM_046922456.1 → XP_046778412.1  thrombopoietin receptor isoform X2

    UniProtKB/TrEMBL
    Q6IYE8

  3. XM_046922449.1 → XP_046778405.1  thrombopoietin receptor isoform X9

    UniProtKB/TrEMBL
    Q6IYE8

  4. XM_046922450.1 → XP_046778406.1  thrombopoietin receptor isoform X10

    UniProtKB/TrEMBL
    Q6IYE8

  5. XM_046922452.1 → XP_046778408.1  thrombopoietin receptor isoform X12

  6. XM_046922451.1 → XP_046778407.1  thrombopoietin receptor isoform X11

    UniProtKB/TrEMBL
    Q6IYE8

  7. XM_046922453.1 → XP_046778409.1  thrombopoietin receptor isoform X13

    UniProtKB/TrEMBL
    Q6IYE8

  8. XM_046922454.1 → XP_046778410.1  thrombopoietin receptor isoform X14

    UniProtKB/TrEMBL
    Q6IYE8
Nucleotide Protein
Heading Accession and Version

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