U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

AvBD4 avian beta-defensin 4 [ Gallus gallus (chicken) ]

Gene ID: 414342, updated on 17-Aug-2024
Symbol
AvBD4provided by CGNC
Full Name
avian beta-defensin 4provided by CGNC
Primary source
CGNC:49916
See related
Ensembl:ENSGALG00010007875
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
GAL4; Gal7; GAL 4; Gal-7; gal-4
NEW
Try the new Gene table
Try the new Transcript table
See AvBD4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (107271812..107273681, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (107034596..107036465, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene avian beta-defensin 3 Neighboring gene avian beta-defensin 5 Neighboring gene avian beta-defensin 14 Neighboring gene XK related 5 Neighboring gene translocation associated membrane protein 2 Neighboring gene EF-hand domain containing 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Antimicrobial activities of chicken β-defensin (4 and 10) peptides against pathogenic bacteria and fungi. Yacoub HA, et al. Front Cell Infect Microbiol, 2015. PMID 25941665, Free PMC Article
  2. Association of three beta-defensin gene (AvBD4, AvBD5, AvBD14) polymorphisms with carrier-state susceptibility to salmonella in chickens. Zhang LY, et al. Br Poult Sci, 2020 Aug. PMID 32290685
  3. The chicken host peptides, gallinacins 4, 7, and 9 have antimicrobial activity against Salmonella serovars. Milona P, et al. Biochem Biophys Res Commun, 2007 Apr 27. PMID 17346671
  4. Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken. Lynn DJ, et al. Immunogenetics, 2004 Jun. PMID 15148642
  5. A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins. Xiao Y, et al. BMC Genomics, 2004 Aug 13. PMID 15310403, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Association of three beta-defensin gene (AvBD4, AvBD5, AvBD14) polymorphisms with carrier-state susceptibility to salmonella in chickens.
    Title: Association of three beta-defensin gene (AvBD4, AvBD5, AvBD14) polymorphisms with carrier-state susceptibility to salmonella in chickens.
  2. The chicken genome encodes only beta-defensins. The 13 chicken beta-defensin genes are clustered densely within a 86-Kb distance on the chromosome 3q3.5-q3.7. The deduced peptides share the characteristic defensin motif.
    Title: A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins.
Submit: New GeneRIF Correction

Homology

Preferred Names
gallinacin-4
Names
beta-defensin 4 antimicrobial peptide
gallinacin-7

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001610.2 → NP_001001610.1  gallinacin-4 prepropeptide precursor

    See identical proteins and their annotated locations for NP_001001610.1

    Status: PROVISIONAL

    Source sequence(s)
    AY621306
    UniProtKB/Swiss-Prot
    Q0PXU4, Q6GXJ1, Q6QLR0
    UniProtKB/TrEMBL
    A0A8V0XQ07
    Related
    ENSGALP00010010289.1, ENSGALT00010018739.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    107271812..107273681 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    107034596..107036465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6GXJ1.1 GenPept UniProtKB/Swiss-Prot:Q6GXJ1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.