LEAP2 liver enriched antimicrobial peptide 2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: LEAP2provided by CGNC
Full Name: liver enriched antimicrobial peptide 2provided by CGNC
Primary source: CGNC:5360
See related: Ensembl:ENSGALG00010013704
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: all
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Genomic context

Location:: chromosome: 13

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	13	NC_052544.1 (16681046..16683112)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	13	NC_052585.1 (16693146..16695213)

Chromosome 13 - NC_052544.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Tissue-, age- and dose-dependent changes in avian beta-defensin and LEAP2 mRNA abundance in the intestines of Salmonella Typhimurium challenged broilers.
Title: Tissue-, age- and dose-dependent changes in avian β-defensin and LEAP2 mRNA abundance in the intestines of Salmonella Typhimurium challenged broilers.
These data provide further support for mature cLEAP-2 functioning in protecting the chicken against microbial attack.
Title: The interaction of the antimicrobial peptide cLEAP-2 and the bacterial membrane.

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General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide	IEA Inferred from Electronic Annotation more info	PubMed
involved_in defense response to bacterium	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: liver-expressed antimicrobial peptide 2

Names: liver expressed antimicrobial peptide 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.