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MAP4 microtubule associated protein 4 [ Homo sapiens (human) ]

Gene ID: 4134, updated on 5-Sep-2021

Summary

Official Symbol
MAP4provided by HGNC
Official Full Name
microtubule associated protein 4provided by HGNC
Primary source
HGNC:HGNC:6862
See related
Ensembl:ENSG00000047849 MIM:157132
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Expression
Ubiquitous expression in heart (RPKM 53.7), brain (RPKM 28.3) and 23 other tissues See more
Orthologs
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Genomic context

See MAP4 in Genome Data Viewer
Location:
3p21.31
Exon count:
29
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (47850695..48089272, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (47892185..48130338, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 Neighboring gene Sharpr-MPRA regulatory region 56 Neighboring gene DExH-box helicase 30 Neighboring gene microRNA 1226 Neighboring gene VPS26B pseudogene 1 Neighboring gene RNA, 7SL, cytoplasmic 664, pseudogene Neighboring gene ribosomal protein L17 pseudogene 16

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
GeneReviews: Not available

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of microtubule-associated protein 4 (MAP4) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed
Knockdown of DNAL1 and MAP4 by siRNAs and shRNAs inhibits HIV-1 replication in HeLa P4.2 cells by blocking reverse transcription and 2-LTR formation PubMed
Knockdown of microtubule-associated protein 4 (MAP4) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

Protein interactions

Protein Gene Interaction Pubs
Pr55(Gag) gag Cellular biotinylated microtubule-associated protein 4 (MAP4) is incorporated into HIV-1 Gag virus-like particles PubMed
gag Interaction of HIV-1 Gag with microtubule-associated protein 4 (MAP4) is identified in a series of six affinity purification/mass spectrometry screens PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC8617, DKFZp779A1753

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables structural molecule activity TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in axon ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in axoneme IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
part_of microtubule associated complex TAS
Traceable Author Statement
more info
PubMed 
located_in microtubule cytoskeleton IDA
Inferred from Direct Assay
more info
 
located_in mitotic spindle IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
microtubule-associated protein 4
Names
MAP-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_052840.1 RefSeqGene

    Range
    5432..243585
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001134364.2NP_001127836.1  microtubule-associated protein 4 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks an alternate exon and uses an alternate splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 4) has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AA904866, AB209377, DA114613
    Consensus CDS
    CCDS46818.1
    UniProtKB/Swiss-Prot
    P27816
    Related
    ENSP00000379083.3, ENST00000395734.7
    Conserved Domains (1) summary
    pfam00418
    Location:9921021
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  2. NM_001384675.1NP_001371604.1  microtubule-associated protein 4 isoform 92

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  3. NM_001384676.1NP_001371605.1  microtubule-associated protein 4 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9771007
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  4. NM_001384677.1NP_001371606.1  microtubule-associated protein 4 isoform 74

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:653930
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:939969
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  5. NM_001384678.1NP_001371607.1  microtubule-associated protein 4 isoform 55

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:587931
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:966996
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  6. NM_001384679.1NP_001371608.1  microtubule-associated protein 4 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:686975
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9941024
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  7. NM_001384680.1NP_001371609.1  microtubule-associated protein 4 isoform 86

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:473817
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:890920
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  8. NM_001384681.1NP_001371610.1  microtubule-associated protein 4 isoform 56

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:951981
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  9. NM_001384707.1NP_001371636.1  microtubule-associated protein 4 isoform 62

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534852
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:926956
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  10. NM_001384729.1NP_001371658.1  microtubule-associated protein 4 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9921022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  11. NM_001384730.1NP_001371659.1  microtubule-associated protein 4 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:969999
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  12. NM_001384731.1NP_001371660.1  microtubule-associated protein 4 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9941024
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  13. NM_001384733.1NP_001371662.1  microtubule-associated protein 4 isoform 81

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:653905
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:929959
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  14. NM_001384734.1NP_001371663.1  microtubule-associated protein 4 isoform 40

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  15. NM_001384735.1NP_001371664.1  microtubule-associated protein 4 isoform 63

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  16. NM_001384736.1NP_001371665.1  microtubule-associated protein 4 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:10091039
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  17. NM_001384737.1NP_001371666.1  microtubule-associated protein 4 isoform 32

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575893
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:967997
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  18. NM_001384738.1NP_001371667.1  microtubule-associated protein 4 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:587931
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:10041034
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  19. NM_001384744.1NP_001371673.1  microtubule-associated protein 4 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:551895
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:968998
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  20. NM_001384745.1NP_001371674.1  microtubule-associated protein 4 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:699948
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:10211051
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  21. NM_001384746.1NP_001371675.1  microtubule-associated protein 4 isoform 70

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:511855
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  22. NM_001384748.1NP_001371677.1  microtubule-associated protein 4 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:587931
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:10041034
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  23. NM_001384751.1NP_001371680.1  microtubule-associated protein 4 isoform 66

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:953982
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  24. NM_001384752.1NP_001371681.1  microtubule-associated protein 4 isoform 106

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:575852
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:721995
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:882912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  25. NM_001384753.1NP_001371682.1  microtubule-associated protein 4 isoform 87

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:589885
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:888918
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  26. NM_001384754.1NP_001371683.1  microtubule-associated protein 4 isoform 38

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9921022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  27. NM_001384755.1NP_001371684.1  microtubule-associated protein 4 isoform 94

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  28. NM_001384756.1NP_001371685.1  microtubule-associated protein 4 isoform 39

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9771007
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  29. NM_001384757.1NP_001371686.1  microtubule-associated protein 4 isoform 104

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:511855
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:890920
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  30. NM_001384758.1NP_001371687.1  microtubule-associated protein 4 isoform 100

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:901931
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  31. NM_001384759.1NP_001371688.1  microtubule-associated protein 4 isoform 112

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:612864
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:873903
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  32. NM_001384760.1NP_001371689.1  microtubule-associated protein 4 isoform 120

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:534811
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:680954
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:841871
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  33. NM_001384761.1NP_001371690.1  microtubule-associated protein 4 isoform 83

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:653905
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:929959
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  34. NM_001384762.1NP_001371691.1  microtubule-associated protein 4 isoform 127

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:197511
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:546576
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  35. NM_001384774.1NP_001371703.1  microtubule-associated protein 4 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9771007
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  36. NM_001384776.1NP_001371705.1  microtubule-associated protein 4 isoform

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:935965
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  37. NM_001384777.1NP_001371706.1  microtubule-associated protein 4 isoform 52

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:969999
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  38. NM_001384778.1NP_001371707.1  microtubule-associated protein 4 isoform 122

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:364708
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:781811
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  39. NM_001384779.1NP_001371708.1  microtubule-associated protein 4 isoform 69

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:679917
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:920950
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  40. NM_001384780.1NP_001371709.1  microtubule-associated protein 4 isoform 84

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:656894
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:897927
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  41. NM_001384781.1NP_001371710.1  microtubule-associated protein 4 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9921022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  42. NM_001384782.1NP_001371711.1  microtubule-associated protein 4 isoform 41

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  43. NM_001384783.1NP_001371712.1  microtubule-associated protein 4 isoform 80

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:630907
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:931961
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  44. NM_001384784.1NP_001371713.1  microtubule-associated protein 4 isoform 132

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:205446
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:459489
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  45. NM_001384785.1NP_001371714.1  microtubule-associated protein 4 isoform 116

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    pfam05109
    Location:665980
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:867897
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  46. NM_001384786.1NP_001371715.1  microtubule-associated protein 4 isoform 58

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:931961
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  47. NM_001384787.1NP_001371716.1  microtubule-associated protein 4 isoform 117

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:552829
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:698972
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:859889
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  48. NM_001384788.1NP_001371717.1  microtubule-associated protein 4 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:10091039
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  49. NM_001384789.1NP_001371718.1  microtubule-associated protein 4 isoform 119

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    pfam05109
    Location:641956
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:843873
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  50. NM_001384790.1NP_001371719.1  microtubule-associated protein 4 isoform 50

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9711001
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  51. NM_001384791.1NP_001371720.1  microtubule-associated protein 4 isoform 28

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:551895
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:968998
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  52. NM_001384792.1NP_001371721.1  microtubule-associated protein 4 isoform 49

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9711001
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  53. NM_001384793.1NP_001371722.1  microtubule-associated protein 4 isoform 105

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:629881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:890920
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  54. NM_001384794.1NP_001371723.1  microtubule-associated protein 4 isoform 82

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK13914
    Location:673889
    PRK13914; invasion associated endopeptidase
    pfam00418
    Location:899929
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  55. NM_001384795.1NP_001371724.1  microtubule-associated protein 4 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:604948
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:93260
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:10211051
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  56. NM_001384796.1NP_001371725.1  microtubule-associated protein 4 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9711001
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  57. NM_001384797.1NP_001371726.1  microtubule-associated protein 4 isoform 43

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:551895
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:953983
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  58. NM_001384798.1NP_001371727.1  microtubule-associated protein 4 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9921022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  59. NM_001384800.1NP_001371729.1  microtubule-associated protein 4 isoform 75

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:939969
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  60. NM_001384802.1NP_001371731.1  microtubule-associated protein 4 isoform 128

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:180429
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:502532
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  61. NM_001384803.1NP_001371732.1  microtubule-associated protein 4 isoform 110

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:496840
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:875905
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  62. NM_001384804.1NP_001371733.1  microtubule-associated protein 4 isoform 73

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03307
    Location:532910
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam00418
    Location:912942
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  63. NM_001384805.1NP_001371734.1  microtubule-associated protein 4 isoform 121

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:534811
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:680954
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:841871
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  64. NM_001384806.1NP_001371735.1  microtubule-associated protein 4 isoform 71

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  65. NM_001384807.1NP_001371736.1  microtubule-associated protein 4 isoform 111

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:496840
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:875905
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  66. NM_001384808.1NP_001371737.1  microtubule-associated protein 4 isoform 129

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:180429
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:502532
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  67. NM_001384809.1NP_001371738.1  microtubule-associated protein 4 isoform 108

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:575852
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:721995
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:882912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  68. NM_001384810.1NP_001371739.1  microtubule-associated protein 4 isoform 65

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  69. NM_001384811.1NP_001371740.1  microtubule-associated protein 4 isoform 118

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:552829
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:698972
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:859889
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  70. NM_001384812.1NP_001371741.1  microtubule-associated protein 4 isoform 133

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:180429
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:449479
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  71. NM_001384813.1NP_001371742.1  microtubule-associated protein 4 isoform 125

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:219554
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:558588
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  72. NM_001384814.1NP_001371743.1  microtubule-associated protein 4 isoform 44

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  73. NM_001384815.1NP_001371744.1  microtubule-associated protein 4 isoform 131

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:180429
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:464494
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  74. NM_001384816.1NP_001371745.1  microtubule-associated protein 4 isoform 27

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:969999
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  75. NM_001384817.1NP_001371746.1  microtubule-associated protein 4 isoform 130

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:156445
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:464494
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  76. NM_001384819.1NP_001371748.1  microtubule-associated protein 4 isoform 76

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  77. NM_001384820.1NP_001371749.1  microtubule-associated protein 4 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575893
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:967997
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  78. NM_001384824.1NP_001371753.1  microtubule-associated protein 4 isoform 59

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:653905
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:929959
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  79. NM_001384825.1NP_001371754.1  microtubule-associated protein 4 isoform 88

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:916946
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  80. NM_001384826.1NP_001371755.1  microtubule-associated protein 4 isoform 113

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:606817
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:841871
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  81. NM_001384827.1NP_001371756.1  microtubule-associated protein 4 isoform 79

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:653906
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:930960
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  82. NM_001384828.1NP_001371757.1  microtubule-associated protein 4 isoform 57

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:931961
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  83. NM_001384831.1NP_001371760.1  microtubule-associated protein 4 isoform 77

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK13914
    Location:656900
    PRK13914; invasion associated endopeptidase
    pfam00418
    Location:905935
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  84. NM_001384832.1NP_001371761.1  microtubule-associated protein 4 isoform 45

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  85. NM_001384834.1NP_001371763.1  microtubule-associated protein 4 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:545889
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:962992
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  86. NM_001384835.1NP_001371764.1  microtubule-associated protein 4 isoform 134

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:166368
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:392422
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  87. NM_001384836.1NP_001371765.1  microtubule-associated protein 4 isoform 48

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:951981
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  88. NM_001384837.1NP_001371766.1  microtubule-associated protein 4 isoform 54

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:936966
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  89. NM_001384838.1NP_001371767.1  microtubule-associated protein 4 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575910
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9831013
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  90. NM_001384839.1NP_001371768.1  microtubule-associated protein 4 isoform 89

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:468812
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:885915
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  91. NM_001384840.1NP_001371769.1  microtubule-associated protein 4 isoform 95

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:647858
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:882912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  92. NM_001384841.1NP_001371770.1  microtubule-associated protein 4 isoform 102

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:901931
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  93. NM_001384842.1NP_001371771.1  microtubule-associated protein 4 isoform 114

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:600838
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:841871
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  94. NM_001384843.1NP_001371772.1  microtubule-associated protein 4 isoform 72

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:496840
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  95. NM_001384844.1NP_001371773.1  microtubule-associated protein 4 isoform 109

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:575852
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:721995
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:882912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  96. NM_001384845.1NP_001371774.1  microtubule-associated protein 4 isoform 101

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:468812
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:870900
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  97. NM_001384846.1NP_001371775.1  microtubule-associated protein 4 isoform 51

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:939969
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  98. NM_001384847.1NP_001371776.1  microtubule-associated protein 4 isoform 67

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:679917
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:920950
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  99. NM_001384848.1NP_001371777.1  microtubule-associated protein 4 isoform 65

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  100. NM_001384849.1NP_001371778.1  microtubule-associated protein 4 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:562906
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9791009
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  101. NM_001384850.1NP_001371779.1  microtubule-associated protein 4 isoform 61

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534852
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:926956
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  102. NM_001384851.1NP_001371780.1  microtubule-associated protein 4 isoform 97

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:641879
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:882912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  103. NM_001384853.1NP_001371782.1  microtubule-associated protein 4 isoform 85

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:898928
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  104. NM_001384856.1NP_001371785.1  microtubule-associated protein 4 isoform 124

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:364708
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:743773
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  105. NM_001384857.1NP_001371786.1  microtubule-associated protein 4 isoform 90

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:916946
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  106. NM_001384859.1NP_001371788.1  microtubule-associated protein 4 isoform 98

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:549893
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  107. NM_001384861.1NP_001371790.1  microtubule-associated protein 4 isoform 115

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    pfam05109
    Location:665980
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam00418
    Location:867897
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  108. NM_001384862.1NP_001371791.1  microtubule-associated protein 4 isoform 123

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:505757
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:781811
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  109. NM_001384863.1NP_001371792.1  microtubule-associated protein 4 isoform 47

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:603947
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9821012
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  110. NM_001384864.1NP_001371793.1  microtubule-associated protein 4 isoform 60

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:511855
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:928958
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  111. NM_001384866.1NP_001371795.1  microtubule-associated protein 4 isoform 99

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:638876
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:879909
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  112. NM_001384867.1NP_001371796.1  microtubule-associated protein 4 isoform 91

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:468812
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:885915
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  113. NM_001384868.1NP_001371797.1  microtubule-associated protein 4 isoform 46

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:951981
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  114. NM_001384869.1NP_001371798.1  microtubule-associated protein 4 isoform 78

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:552896
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:931961
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  115. NM_001384870.1NP_001371799.1  microtubule-associated protein 4 isoform 93

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:647858
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:882912
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  116. NM_001384871.1NP_001371800.1  microtubule-associated protein 4 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575894
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:968998
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  117. NM_001384872.1NP_001371801.1  microtubule-associated protein 4 isoform 68

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:665942
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:951981
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  118. NM_001384873.1NP_001371802.1  microtubule-associated protein 4 isoform 33

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:549893
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:966996
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  119. NM_001384874.1NP_001371803.1  microtubule-associated protein 4 isoform 64

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:545889
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:924954
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  120. NM_001384875.1NP_001371804.1  microtubule-associated protein 4 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:587931
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:9891019
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  121. NM_001384876.1NP_001371805.1  microtubule-associated protein 4 isoform 42

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:537881
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  122. NM_001384877.1NP_001371806.1  microtubule-associated protein 4 isoform 126

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:198470
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:543573
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  123. NM_001384878.1NP_001371807.1  microtubule-associated protein 4 isoform 96

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:572878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:913943
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  124. NM_001384879.1NP_001371808.1  microtubule-associated protein 4 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9921022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  125. NM_001384892.1NP_001371821.1  microtubule-associated protein 4 isoform 37

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:545889
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:962992
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  126. NM_001384893.1NP_001371822.1  microtubule-associated protein 4 isoform 103

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:534878
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:898928
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  127. NM_001385664.1NP_001372593.1  microtubule-associated protein 4 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:17752024
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:20592089
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  128. NM_001385665.1NP_001372594.1  microtubule-associated protein 4 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9921022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  129. NM_001385675.1NP_001372604.1  microtubule-associated protein 4 isoform 34

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (3) summary
    PHA03247
    Location:587931
    PHA03247; large tegument protein UL36; Provisional
    COG3456
    Location:76243
    COG3456; Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport]
    pfam00418
    Location:966996
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  130. NM_001385676.1NP_001372605.1  microtubule-associated protein 4 isoform 107

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:615853
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:856886
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  131. NM_001385677.1NP_001372606.1  microtubule-associated protein 4 isoform 44

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:954984
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  132. NM_001385681.1NP_001372610.1  microtubule-associated protein 4 isoform 25

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9711001
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  133. NM_001385682.1NP_001372611.1  microtubule-associated protein 4 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Related
    ENSP00000507895.1, ENST00000683076.1
    Conserved Domains (2) summary
    PHA03247
    Location:18152064
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:21372167
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  134. NM_001385684.1NP_001372613.1  microtubule-associated protein 4 isoform 53

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:939969
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  135. NM_001385685.1NP_001372614.1  microtubule-associated protein 4 isoform 69

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PRK07003
    Location:679917
    PRK07003; DNA polymerase III subunit gamma/tau
    pfam00418
    Location:920950
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  136. NM_001385686.1NP_001372615.1  microtubule-associated protein 4 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:592936
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:10091039
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  137. NM_001385687.1NP_001372616.1  microtubule-associated protein 4 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:18152064
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:21372167
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  138. NM_001385688.1NP_001372617.1  microtubule-associated protein 4 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:18142051
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:20602090
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  139. NM_001385689.1NP_001372618.1  microtubule-associated protein 4 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
    Conserved Domains (2) summary
    PHA03247
    Location:18152064
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:20992129
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  140. NM_001385690.1NP_001372619.1  microtubule-associated protein 4 isoform 135

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
  141. NM_001385691.1NP_001372620.1  microtubule-associated protein 4 isoform 135

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
  142. NM_001385692.1NP_001372621.1  microtubule-associated protein 4 isoform 135

    Status: REVIEWED

    Source sequence(s)
    AC124916, AC139667
  143. NM_002375.5NP_002366.2  microtubule-associated protein 4 isoform 1

    See identical proteins and their annotated locations for NP_002366.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. It encodes the longest isoform (1).
    Source sequence(s)
    AA904866, AB209377, DA114613, M64571
    Consensus CDS
    CCDS33750.1
    UniProtKB/Swiss-Prot
    P27816
    Related
    ENSP00000353375.6, ENST00000360240.10
    Conserved Domains (2) summary
    PHA03247
    Location:575919
    PHA03247; large tegument protein UL36; Provisional
    pfam00418
    Location:9921022
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  144. NM_030885.4NP_112147.2  microtubule-associated protein 4 isoform 3

    See identical proteins and their annotated locations for NP_112147.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks multiple exons in the 3' region and uses an unique splice site at the 3' end-exon compared to variant 1. The resulting isoform (3) has a distinct and shorter C-terminus, as compared to isoform 1.
    Source sequence(s)
    AA206810, AI078534, BC051843, DA114613, DA150735
    Consensus CDS
    CCDS46821.1
    UniProtKB/Swiss-Prot
    P27816
    Related
    ENSP00000397414.1, ENST00000439356.2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    47850695..48089272 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017006397.1XP_016861886.1  microtubule-associated protein 4 isoform X19

  2. XM_011533719.2XP_011532021.1  microtubule-associated protein 4 isoform X15

    Conserved Domains (1) summary
    pfam00418
    Location:10211050
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  3. XM_011533708.2XP_011532010.1  microtubule-associated protein 4 isoform X7

    Conserved Domains (1) summary
    pfam00418
    Location:21342163
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  4. XM_011533718.1XP_011532020.1  microtubule-associated protein 4 isoform X14

    Conserved Domains (2) summary
    pfam05086
    Location:19942152
    Dicty_REP; Dictyostelium (Slime Mold) REP protein
    pfam00418
    Location:21112140
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  5. XM_011533705.1XP_011532007.1  microtubule-associated protein 4 isoform X5

    Related
    ENSP00000407602.2, ENST00000426837.6
    Conserved Domains (1) summary
    pfam00418
    Location:21492178
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  6. XM_024453528.1XP_024309296.1  microtubule-associated protein 4 isoform X13

    Conserved Domains (3) summary
    pfam00418
    Location:21252154
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl00062
    Location:93260
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cl26464
    Location:18422021
    Atrophin-1; Atrophin-1 family
  7. XM_024453527.1XP_024309295.1  microtubule-associated protein 4 isoform X12

    Conserved Domains (3) summary
    pfam00418
    Location:21252154
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl00062
    Location:93260
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cl26464
    Location:18422021
    Atrophin-1; Atrophin-1 family
  8. XM_024453526.1XP_024309294.1  microtubule-associated protein 4 isoform X11

    Conserved Domains (3) summary
    pfam00418
    Location:21512180
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl00062
    Location:93260
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cl26464
    Location:18432132
    Atrophin-1; Atrophin-1 family
  9. XM_017006391.1XP_016861880.1  microtubule-associated protein 4 isoform X4

  10. XM_011533704.2XP_011532006.1  microtubule-associated protein 4 isoform X3

    Conserved Domains (1) summary
    pfam00418
    Location:21512180
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  11. XM_017006392.1XP_016861881.1  microtubule-associated protein 4 isoform X10

  12. XM_011533709.2XP_011532011.1  microtubule-associated protein 4 isoform X9

    Conserved Domains (1) summary
    pfam00418
    Location:21282157
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  13. XM_024453525.1XP_024309293.1  microtubule-associated protein 4 isoform X8

    Conserved Domains (3) summary
    pfam00418
    Location:21662195
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl00062
    Location:93260
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cl26464
    Location:18442093
    Atrophin-1; Atrophin-1 family
  14. XM_024453524.1XP_024309292.1  microtubule-associated protein 4 isoform X6

    Conserved Domains (3) summary
    pfam00418
    Location:21662195
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl00062
    Location:93260
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cl26464
    Location:18442093
    Atrophin-1; Atrophin-1 family
  15. XM_011533703.2XP_011532005.1  microtubule-associated protein 4 isoform X2

    Conserved Domains (1) summary
    pfam00418
    Location:21662195
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  16. XM_024453523.1XP_024309291.1  microtubule-associated protein 4 isoform X1

    Conserved Domains (3) summary
    pfam00418
    Location:21972226
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    cl00062
    Location:93260
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cl26464
    Location:18442093
    Atrophin-1; Atrophin-1 family
  17. XM_017006396.2XP_016861885.1  microtubule-associated protein 4 isoform X18

RNA

  1. XR_002959533.1 RNA Sequence

  2. XR_002959534.1 RNA Sequence

  3. XR_002959532.1 RNA Sequence

  4. XR_002959526.1 RNA Sequence

  5. XR_002959528.1 RNA Sequence

  6. XR_002959524.1 RNA Sequence

  7. XR_002959530.1 RNA Sequence

  8. XR_002959522.1 RNA Sequence

  9. XR_002959520.1 RNA Sequence

  10. XR_002959527.1 RNA Sequence

  11. XR_002959523.1 RNA Sequence

  12. XR_002959525.1 RNA Sequence

  13. XR_002959521.1 RNA Sequence

  14. XR_002959531.1 RNA Sequence

  15. XR_002959529.1 RNA Sequence

  16. XR_002959519.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001134365.1: Suppressed sequence

    Description
    NM_001134365.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
  2. NM_030884.3: Suppressed sequence

    Description
    NM_030884.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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