Format

Send to:

Choose Destination

Mcm5 Minichromosome maintenance 5 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41296, updated on 4-Nov-2018

Summary

Official Symbol
Mcm5provided by FlyBase
Official Full Name
Minichromosome maintenance 5provided by FlyBase
Primary source
FLYBASE:FBgn0017577
Locus tag
Dmel_CG4082
Gene type
protein coding
RNA name
minichromosome maintenance 5
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4082; DmCDC46; DmCDC465; Dmel\CG4082; DmeMCM5; DmMcm5; DmMCM5; mcm5; McM5; MCM5; PCR4

Genomic context

See Mcm5 in Genome Data Viewer
Location:
86C6-86C6; 3-50 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10788524..10791150)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6614246..6616872)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene RNA-binding protein 1 Neighboring gene Arginine methyltransferase 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Mcm5 gene: The Mcm5 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to 3'-5' DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA replication origin binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA endoreduplication IMP
Inferred from Mutant Phenotype
more info
PubMed 
DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 
chromosome condensation IMP
Inferred from Mutant Phenotype
more info
PubMed 
meiotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
resolution of meiotic recombination intermediates IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
MCM complex IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
minichromosome maintenance 5
Names
CG4082-PA
Mcm5-PA
mini-chromosome maintenance 5

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    10788524..10791150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079584.4NP_524308.2  minichromosome maintenance 5 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524308.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VGW6
    Related
    FBpp0081756, FBtr0082279
    Conserved Domains (3) summary
    cd00009
    Location:366517
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00350
    Location:128648
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:33148
    MCM_N; MCM N-terminal domain
Support Center