CG6345 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG6345provided by FlyBase
Primary source: FLYBASE:FBgn0037816
Locus tag: Dmel_CG6345
See related: AllianceGenome:FB:FBgn0037816
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 149631_at; Dmel\CG6345
Summary: Predicted to enable N6-isopentenyladenosine methylthiotransferase activity. Predicted to be involved in negative regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including anterior endoderm anlage; dorsal pharyngeal muscle cell; embryonic Malpighian tubule; gastrula embryo; and germ layer derivative. Orthologous to human CDK5RAP1 (CDK5 regulatory subunit associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (10414218..10416046, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (6239940..6241768, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables 4 iron, 4 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables N6-isopentenyladenosine methylthiotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables iron-sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables methylthiotransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in negative regulation of cyclin-dependent protein serine/threonine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cyclin-dependent protein serine/threonine kinase activity	ISS Inferred from Sequence or Structural Similarity more info
involved_in tRNA modification	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

NP_650002.1

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The following sections contain reference sequences that belong to a specific genome build. Explain