Format

Send to:

Choose Destination

Rrp46 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41270, updated on 10-Jan-2019

Summary

Official Symbol
Rrp46provided by FlyBase
Primary source
FLYBASE:FBgn0037815
Locus tag
Dmel_CG4043
Gene type
protein coding
RNA name
Rrp46
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4043; Dmel\CG4043; dRrp46; rrp46

Genomic context

See Rrp46 in Genome Data Viewer
Location:
86B4-86B4; 3-49 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.18 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10413301..10414242)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6239023..6239964)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene mir-318 stem loop Neighboring gene Iron regulatory protein 1B Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cyp12e1

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the Rrp46 gene: The Rrp46 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, E.gossypii, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
U4 snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear mRNA surveillance IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
polyadenylation-dependent snoRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
rRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
exosome (RNase complex) IDA
Inferred from Direct Assay
more info
PubMed 
nuclear exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear exosome (RNase complex) IDA
Inferred from Direct Assay
more info
PubMed 
nuclear exosome (RNase complex) ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Rrp46
Names
CG4043-PA
Rrp46-PA

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    10413301..10414242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141744.3NP_650001.2  Rrp46 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650001.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VGZ2
    Related
    FBpp0081725, FBtr0082248
    Conserved Domains (2) summary
    cd11372
    Location:14211
    RNase_PH_RRP46; RRP46 subunit of eukaryotic exosome
    COG0689
    Location:10215
    Rph; Ribonuclease PH [Translation, ribosomal structure and biogenesis]
Support Center