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Mical Molecule interacting with CasL [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41225, updated on 10-Oct-2019

Summary

Official Symbol
Micalprovided by FlyBase
Official Full Name
Molecule interacting with CasLprovided by FlyBase
Primary source
FLYBASE:FBgn0053208
Locus tag
Dmel_CG33208
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11685; CG11687; CG18484; CG18667; CG18668; CG33186; CG33190; CG33208; Dmel\CG33208; mdcds_49226; mical; MICAL; milch

Genomic context

See Mical in Genome Data Viewer
Location:
85F5-85F7; 3-49 cM
Exon count:
28
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10001554..10042895, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5827276..5868617, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 85a Neighboring gene Serpin 85F Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mitochondrial transcription factor B2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin filament depolymerization IDA
Inferred from Direct Assay
more info
PubMed 
actin filament depolymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
actin filament organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
actin modification IDA
Inferred from Direct Assay
more info
PubMed 
axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
axon guidance TAS
Traceable Author Statement
more info
PubMed 
dendrite morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron remodeling IGI
Inferred from Genetic Interaction
more info
PubMed 
neuron remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
oxidation-reduction process IDA
Inferred from Direct Assay
more info
PubMed 
regulation of neuron remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
sarcomere organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
skeletal muscle thin filament assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
synapse assembly involved in innervation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytosol NAS
Non-traceable Author Statement
more info
PubMed 
filamentous actin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule organizing center IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
terminal bouton IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
molecule interacting with CasL
Names
CG33208-PA
CG33208-PB
CG33208-PC
CG33208-PD
CG33208-PE
CG33208-PF
CG33208-PG
CG33208-PI
CG33208-PK
CG33208-PL
CG33208-PN
CG33208-PO
CG33208-PP
CG33208-PQ
Mical-PA
Mical-PB
Mical-PC
Mical-PD
Mical-PE
Mical-PF
Mical-PG
Mical-PI
Mical-PK
Mical-PL
Mical-PN
Mical-PO
Mical-PP
Mical-PQ
mical
milchstrasse
molecule that interacts with CasL
NP_001138032.1
NP_001247014.1
NP_001247015.1
NP_001247016.2
NP_001303502.1
NP_001303503.1
NP_788620.1
NP_788621.1
NP_788622.1
NP_788623.1
NP_788624.1
NP_788625.1
NP_788626.2
NP_788627.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    10001554..10042895 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001260086.3NP_001247015.1  molecule interacting with CasL, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247015.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K6D5
    Related
    FBpp0297564, FBtr0306609
    Conserved Domains (5) summary
    pfam09528
    Location:20812479
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    cd09439
    Location:10971153
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:45924705
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  2. NM_001260085.2NP_001247014.1  molecule interacting with CasL, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247014.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K703
    Related
    FBpp0297563, FBtr0306608
    Conserved Domains (5) summary
    pfam09528
    Location:20812479
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    cd09439
    Location:10971153
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:45814694
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  3. NM_176443.2NP_788620.1  molecule interacting with CasL, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788620.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86BA1
    Related
    FBpp0081686, FBtr0082208
    Conserved Domains (4) summary
    cd09439
    Location:806862
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:25832696
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  4. NM_001316574.1NP_001303503.1  molecule interacting with CasL, isoform Q [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A126GUS6
    Related
    FBpp0312512, FBtr0347214
    Conserved Domains (4) summary
    cd09439
    Location:10741130
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:28402953
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  5. NM_176444.2NP_788621.1  molecule interacting with CasL, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788621.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86BA1
    Related
    FBpp0081685, FBtr0082207
    Conserved Domains (4) summary
    cd09439
    Location:10741130
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:28512964
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  6. NM_001260087.3NP_001247016.2  molecule interacting with CasL, isoform N [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K6N6
    Related
    FBpp0312509, FBtr0347211
    Conserved Domains (4) summary
    pfam09528
    Location:20612459
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    cd09439
    Location:10741130
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  7. NM_001316573.1NP_001303502.1  molecule interacting with CasL, isoform P [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A126GUS4
    Related
    FBpp0312511, FBtr0347213
    Conserved Domains (5) summary
    pfam09528
    Location:20612459
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    cd09439
    Location:10741130
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:45384651
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  8. NM_176447.2NP_788624.1  molecule interacting with CasL, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788624.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86BA1
    Related
    FBpp0081687, FBtr0082209
    Conserved Domains (5) summary
    pfam09528
    Location:20612459
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    cd09439
    Location:10741130
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:45724685
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  9. NM_176445.2NP_788622.1  molecule interacting with CasL, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788622.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86BA1
    Related
    FBpp0081688, FBtr0082210
    Conserved Domains (5) summary
    pfam09528
    Location:20612459
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    cd09439
    Location:10741130
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:45724685
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  10. NM_176449.3NP_788626.2  molecule interacting with CasL, isoform O [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86BA1
    Related
    FBpp0312510, FBtr0347212
    Conserved Domains (5) summary
    pfam09528
    Location:20612459
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    cd09439
    Location:10741130
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:45494662
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  11. NM_176448.2NP_788625.1  molecule interacting with CasL, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788625.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86BA1
    Related
    FBpp0081690, FBtr0082212
    Conserved Domains (5) summary
    pfam09528
    Location:20612459
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    cd09439
    Location:10741130
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:45724685
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  12. NM_176446.2NP_788623.1  molecule interacting with CasL, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788623.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86BA1
    Related
    FBpp0081691, FBtr0082213
    Conserved Domains (5) summary
    pfam09528
    Location:20612459
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    cd09439
    Location:10741130
    LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
    pfam12130
    Location:45724685
    DUF3585; Protein of unknown function (DUF3585)
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
  13. NM_176450.1NP_788627.1  molecule interacting with CasL, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788627.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86BA1
    Related
    FBpp0081684, FBtr0082206
    Conserved Domains (3) summary
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
    cl21454
    Location:131255
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
  14. NM_001144560.3NP_001138032.1  molecule interacting with CasL, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138032.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86BA1
    Related
    FBpp0271693, FBtr0273185
    Conserved Domains (3) summary
    cl00030
    Location:563629
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cl16912
    Location:114160
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family
    cl21454
    Location:131255
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
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