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Prosbeta3 Proteasome beta3 subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41079, updated on 17-Nov-2020

Summary

Official Symbol
Prosbeta3provided by FlyBase
Official Full Name
Proteasome beta3 subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0026380
Locus tag
Dmel_CG11981
Gene type
protein coding
RNA name
proteasome beta3 subunit
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
11981; beta-3; Beta-3; beta3; CG11981; Dmel\CG11981; Pros beta3

Genomic context

See Prosbeta3 in Genome Data Viewer
Location:
85C2-85C2; 3-48 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9005313..9006226, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4831035..4831948, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Iruka Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Prosbeta3 gene: The Prosbeta3 gene is conserved in human, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to endopeptidase activity IC
Inferred by Curator
more info
PubMed 
threonine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome complex IDA
Inferred from Direct Assay
more info
PubMed 
proteasome core complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome core complex IDA
Inferred from Direct Assay
more info
PubMed 
proteasome core complex, beta-subunit complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
proteasome beta3 subunit
Names
20S proteasome beta3 subunit
20s proteasome
CG11981-PA
Prosbeta3-PA
beta3
NP_649858.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    9005313..9006226 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141601.2NP_649858.1  proteasome beta3 subunit [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649858.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XYN7
    UniProtKB/TrEMBL
    C0MJU2
    Related
    FBpp0081488, FBtr0082010
    Conserved Domains (2) summary
    COG0638
    Location:6198
    PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
    cd03759
    Location:6201
    proteasome_beta_type_3; proteasome beta type-3 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
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