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CG8223 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41045, updated on 30-Nov-2022

Summary

Official Symbol
CG8223provided by FlyBase
Primary source
FLYBASE:FBgn0037624
Locus tag
Dmel_CG8223
See related
AllianceGenome:FB:FBgn0037624
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8223; FBgn0037624
Summary
Predicted to enable histone binding activity. Predicted to be involved in CENP-A containing chromatin assembly and DNA replication-dependent chromatin assembly. Located in nucleus. Is expressed in several structures, including anterior endoderm anlage; embryonic brain; extended germ band embryo; germline cell; and lateral cord neurons. Orthologous to human NASP (nuclear autoantigenic sperm protein). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See CG8223 in Genome Data Viewer
Location:
85A10-85A10; 3-48 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.46 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8747798..8754104)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4573520..4579826)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44228 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in CENP-A containing chromatin assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in DNA replication-dependent chromatin assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus HDA PubMed 

General protein information

Preferred Names
uncharacterized protein
Names
CG8223-PA
CG8223-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8747798..8754104
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001260064.2NP_001246993.1  uncharacterized protein Dmel_CG8223, isoform B [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9I7K6
    UniProtKB/TrEMBL
    A0A126BEE6
    Related
    FBpp0301016, FBtr0308889
    Conserved Domains (2) summary
    sd00006
    Location:283313
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:281352
    TPR_12; Tetratricopeptide repeat
  2. NM_141571.5NP_649828.1  uncharacterized protein Dmel_CG8223, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649828.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9I7K6
    UniProtKB/TrEMBL
    A0A126BEE6
    Related
    FBpp0081398, FBtr0081915
    Conserved Domains (2) summary
    sd00006
    Location:283313
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:281352
    TPR_12; Tetratricopeptide repeat