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Antp Antennapedia [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40835, updated on 8-Feb-2025

Summary

Official Symbol
Antpprovided by FlyBase
Official Full Name
Antennapediaprovided by FlyBase
Primary source
FLYBASE:FBgn0260642
Locus tag
Dmel_CG1028
See related
AllianceGenome:FB:FBgn0260642
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
3.4; Ant; ANT-C; ANT-P; ANTC; antp; AntP; ANTP; Antp P1; Antp P2; Antp1; AntP1; Aus; BG:DS07700.1; CG1028; DmAntp; DMANTPE1; Dmel\CG1028; DRO15DC96Z; Hu; l(3)84Ba; Ns; Scx
Summary
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including muscle cell fate specification; neuroblast development; and regionalization. Located in cytoplasm and nucleus. Is expressed in several structures, including anterior-posterior subdivision of organism; embryonic segment posterior compartment; imaginal disc; neuroblast NB5-6; and neuromere. Orthologous to several human genes including HOXA7 (homeobox A7). [provided by Alliance of Genome Resources, Feb 2025]
Orthologs
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Genomic context

See Antp in Genome Data Viewer
Location:
84A6-84B2; 3-48 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6896253..6999228, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2721975..2824950, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45559 Neighboring gene long non-coding RNA:CR44932 Neighboring gene long non-coding RNA:CR43252 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45899 Neighboring gene long non-coding RNA:CR44933

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in anterior/posterior axis specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in anterior/posterior axis specification TAS
Traceable Author Statement
more info
PubMed 
involved_in anterior/posterior pattern specification IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in heart development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in lymph gland development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in midgut development TAS
Traceable Author Statement
more info
PubMed 
involved_in muscle cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neuroblast development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of neurogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in specification of segmental identity, antennal segment IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in specification of segmental identity, thorax IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in specification of segmental identity, thorax TAS
Traceable Author Statement
more info
PubMed 
involved_in ventral cord development HMP PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
antennapedia
Names
Antp-PD
Antp-PE
Antp-PF
Antp-PG
Antp-PH
Antp-PI
Antp-PJ
Antp-PK
Antp-PL
Antp-PM
Antp-PN
Antp-PO
Aus
CG1028-PD
CG1028-PE
CG1028-PF
CG1028-PG
CG1028-PH
CG1028-PI
CG1028-PJ
CG1028-PK
CG1028-PL
CG1028-PM
CG1028-PN
CG1028-PO
Dm-Antennapedia
Sex comb extra
Sex combs extra
antenapedia
antennapaedia
antennapedia P1
antennapedia P2
atennapedia
humeral
nasobemia
NP_996167.1
  • unusual splice
NP_996168.1
  • unusual splice
NP_996169.1
  • unusual splice
NP_996170.1
  • unusual splice
NP_996172.1
  • unusual splice
NP_996175.1
  • unusual splice

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    6896253..6999228 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206451.1NP_996173.1  antennapedia, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996173.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D6W4V0, Q7KSY7
    Conserved Domains (2) summary
    TIGR01628
    Location:203277
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    pfam00046
    Location:284337
    Homeobox; Homeobox domain
  2. NM_206450.1NP_996172.1  antennapedia, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996172.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D6W4V0, Q7KSY6
    Conserved Domains (2) summary
    TIGR01628
    Location:203277
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    pfam00046
    Location:288341
    Homeobox; Homeobox domain
  3. NM_206449.1NP_996171.1  antennapedia, isoform N [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996171.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D6W4V0, Q7KSY5
    Conserved Domains (2) summary
    pfam00046
    Location:297350
    Homeobox; Homeobox domain
    cl41729
    Location:161302
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins
  4. NM_206453.1NP_996175.1  antennapedia, isoform M [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996175.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02833, Q95SZ6
    UniProtKB/TrEMBL
    A4V2I6, D6W4V0
    Conserved Domains (2) summary
    pfam00046
    Location:301354
    Homeobox; Homeobox domain
    cl41729
    Location:161306
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins
  5. NM_001382007.1NP_001368996.1  antennapedia, isoform O [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    D6W4V0, Q7KSY6
    Conserved Domains (2) summary
    TIGR01628
    Location:203277
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    pfam00046
    Location:288341
    Homeobox; Homeobox domain
  6. NM_206444.1NP_996166.1  antennapedia, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996166.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D6W4V0, Q7KSY7
    Conserved Domains (2) summary
    TIGR01628
    Location:203277
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    pfam00046
    Location:284337
    Homeobox; Homeobox domain
  7. NM_206447.1NP_996169.1  antennapedia, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996169.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D6W4V0, Q7KSY6
    Conserved Domains (2) summary
    TIGR01628
    Location:203277
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    pfam00046
    Location:288341
    Homeobox; Homeobox domain
  8. NM_206452.1NP_996174.1  antennapedia, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996174.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D6W4V0, Q7KSY5
    Conserved Domains (2) summary
    pfam00046
    Location:297350
    Homeobox; Homeobox domain
    cl41729
    Location:161302
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins
  9. NM_206448.1NP_996170.1  antennapedia, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996170.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02833, Q95SZ6
    UniProtKB/TrEMBL
    A4V2I6, D6W4V0
    Conserved Domains (2) summary
    pfam00046
    Location:301354
    Homeobox; Homeobox domain
    cl41729
    Location:161306
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins
  10. NM_206446.1NP_996168.1  antennapedia, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996168.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02833, Q95SZ6
    UniProtKB/TrEMBL
    A4V2I6, D6W4V0
    Conserved Domains (2) summary
    pfam00046
    Location:301354
    Homeobox; Homeobox domain
    cl41729
    Location:161306
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins
  11. NM_206445.1NP_996167.1  antennapedia, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996167.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02833, Q95SZ6
    UniProtKB/TrEMBL
    A4V2I6, D6W4V0
    Conserved Domains (2) summary
    pfam00046
    Location:301354
    Homeobox; Homeobox domain
    cl41729
    Location:161306
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins
  12. NM_206454.1NP_996176.1  antennapedia, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996176.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02833
    Conserved Domains (1) summary
    TIGR01628
    Location:230285
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family