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Wfdc13 WAP four-disulfide core domain 13 [ Mus musculus (house mouse) ]

Gene ID: 408190, updated on 11-Apr-2024

Summary

Official Symbol
Wfdc13provided by MGI
Official Full Name
WAP four-disulfide core domain 13provided by MGI
Primary source
MGI:MGI:3582777
See related
Ensembl:ENSMUSG00000067704 AllianceGenome:MGI:3582777
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Wfdc13l1
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to act upstream of or within negative regulation of peptidase activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human WFDC13 (WAP four-disulfide core domain 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 377.4) See more
Orthologs
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Genomic context

See Wfdc13 in Genome Data Viewer
Location:
2 H3; 2 85.25 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (164527027..164529626)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (164685107..164687706)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain 9 Neighboring gene WAP four-disulfide core domain 10 Neighboring gene WAP four-disulfide core domain 11 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:164504826-164505027 Neighboring gene serine protease inhibitor, Kunitz type 4 Neighboring gene serine protease inhibitor, Kunitz type 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables peptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in antibacterial humoral response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within negative regulation of peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
WAP four-disulfide core domain protein 13
Names
WAP four-disulfide core domain 13-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012704.1NP_001012722.1  WAP four-disulfide core domain protein 13 precursor

    See identical proteins and their annotated locations for NP_001012722.1

    Status: PROVISIONAL

    Source sequence(s)
    AY542486
    Consensus CDS
    CCDS38327.1
    UniProtKB/Swiss-Prot
    Q5DQQ6, Q6IE33
    Related
    ENSMUSP00000085594.2, ENSMUST00000088260.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    164527027..164529626
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)