adss1 adenylosuccinate synthase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: adss1provided by ZNC
Official Full Name: adenylosuccinate synthase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040516-18
See related: Ensembl:ENSDARG00000099517 AllianceGenome:ZFIN:ZDB-GENE-040516-18
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: AdSS 1; adssl1; zgc:85738
Summary: Predicted to enable adenylosuccinate synthase activity. Acts upstream of or within muscle cell cellular homeostasis and skeletal muscle fiber development. Predicted to be active in cytoplasm. Orthologous to human ADSS1 (adenylosuccinate synthase 1). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 17

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	17	NC_133192.1 (2458337..2491632)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (1323699..1355792)

Chromosome 17 - NC_133192.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fj05h05.x1 (e-PCR)
- UniSTS:198410

G48078 (e-PCR)
- UniSTS:108842

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables adenylosuccinate synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables adenylosuccinate synthase activity	IEA Inferred from Electronic Annotation more info
enables adenylosuccinate synthase activity	ISS Inferred from Sequence or Structural Similarity more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in 'de novo' AMP biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in 'de novo' AMP biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in AMP biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in IMP metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within muscle cell cellular homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in purine nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within skeletal muscle fiber development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: adenylosuccinate synthetase isozyme 1

Names: adenylosuccinate synthase like 1

NP_999985.1

EC 6.3.4.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.