U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

myh4 myosin, heavy chain 4, skeletal muscle [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 407946, updated on 19-Nov-2025
Official Symbol
myh4provided by Xenbase
Official Full Name
myosin, heavy chain 4, skeletal muscleprovided by Xenbase
Primary source
Xenbase:XB-GENE-989283
See related
Ensembl:ENSXETG00000011987 AllianceGenome:Xenbase:XB-GENE-989283
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
E3; mhc; myh2b; myhe3; myhc-2b; myhc-iib
Summary
Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. [provided by Alliance of Genome Resources, Apr 2025]
Try the new Gene page
Try the new Transcripts and proteins table
See myh4 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
41
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (103811615..103826513)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (83534467..83548538)

Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene solute carrier family 35 member F4 Neighboring gene uncharacterized LOC116406768 Neighboring gene coiled-coil domain containing 198 Neighboring gene N(alpha)-acetyltransferase 30, NatC catalytic subunit Neighboring gene 5-hydroxytryptamine receptor 1B

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Clone Names

  • MGC75596

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
  
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
  
enables microfilament motor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in myofibril IEA
Inferred from Electronic Annotation
more info
  
part_of myosin II complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in myosin filament IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in myosin filament IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
myosin, heavy chain 4, skeletal muscle
Names
MHC A7
MHC E3
myhc E3
myosin heavy chain

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001244.1 → NP_001001244.1  myosin, heavy chain 4, skeletal muscle

    See identical proteins and their annotated locations for NP_001001244.1

    Status: PROVISIONAL

    Source sequence(s)
    BC067305
    UniProtKB/TrEMBL
    F6Q5S6, F6UW26, L7N3K1, Q6NX33
    Related
    ENSXETP00000026213.3, ENSXETT00000026213.5
    Conserved Domains (3) summary
    cd01377
    Location:99 → 766
    MYSc_class_II; class II myosins, motor domain
    pfam01576
    Location:846 → 1923
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    103811615..103826513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031890312.1 → XP_031746172.1  myosin, heavy chain 4, skeletal muscle isoform X1

    UniProtKB/TrEMBL
    F6Q5S6, F6UW26, L7N3K1, Q6NX33
    Conserved Domains (3) summary
    cd01377
    Location:99 → 766
    MYSc_class_II; class II myosins, motor domain
    pfam01576
    Location:846 → 1923
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.