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Timd6 T cell immunoglobulin and mucin domain containing 6 [ Mus musculus (house mouse) ]

Gene ID: 407814, updated on 12-May-2024

Summary

Official Symbol
Timd6provided by MGI
Official Full Name
T cell immunoglobulin and mucin domain containing 6provided by MGI
Primary source
MGI:MGI:3039605
See related
Ensembl:ENSMUSG00000046974 AllianceGenome:MGI:3039605
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable phosphatidylserine binding activity and virus receptor activity. Predicted to be involved in phagocytosis, engulfment and positive regulation of mast cell activation. Predicted to be located in motile cilium. Predicted to be active in cell surface. Is expressed in eye; ovary; and testis. Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See Timd6 in Genome Data Viewer
Location:
11 B1.1; 11 28.0 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (46462340..46480059)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (46571513..46589232)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene developmental pluripotency associated 1 family member pseudogene Neighboring gene STARR-seq mESC enhancer starr_29332 Neighboring gene ribosomal protein L9, pseudogene 2 Neighboring gene developmental pluripotency associated 1 Neighboring gene T cell immunoglobulin and mucin domain containing 7, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables phosphatidylserine binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables virus receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables virus receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in phagocytosis, engulfment IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of mast cell activation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in motile cilium ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
uncharacterized protein LOC407814
Names
hepatitis A virus cellular receptor 1-like family member

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025435.3NP_001020606.2  uncharacterized protein LOC407814 precursor

    See identical proteins and their annotated locations for NP_001020606.2

    Status: PREDICTED

    Source sequence(s)
    AL669948
    Consensus CDS
    CCDS24580.1
    UniProtKB/TrEMBL
    A0A0B4J1F6, Q7TQ03
    Related
    ENSMUSP00000050057.7, ENSMUST00000050937.7
    Conserved Domains (2) summary
    smart00410
    Location:23111
    IG_like; Immunoglobulin like
    pfam07686
    Location:30110
    V-set; Immunoglobulin V-set domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    46462340..46480059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)