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IL18R1 interleukin 18 receptor 1 [ Bos taurus (domestic cattle) ]

Gene ID: 407221, updated on 30-Jan-2025
Official Symbol
IL18R1provided by VGNC
Official Full Name
interleukin 18 receptor 1provided by VGNC
Primary source
VGNC:VGNC:30127
See related
BGD:BT11467; EnsemblRapid:ENSBTAG00070035004
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
IL-18Ra
Orthologs
human mouse all
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See IL18R1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (7165279..7194967)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346540 Neighboring gene N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2-like Neighboring gene interleukin 1 receptor like 2 Neighboring gene interleukin 1 receptor like 1 Neighboring gene interleukin 18 receptor accessory protein Neighboring gene U6 spliceosomal RNA Neighboring gene solute carrier family 9 member A4

Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Localization of interleukin-18 and its receptor in somatotrophs of the bovine anterior pituitary gland. Nagai Y, et al. Cell Tissue Res, 2005 Dec. PMID 16001266
  2. Bovine anterior pituitary progenitor cell line expresses interleukin (IL)-18 and IL-18 receptor. Nagai Y, et al. J Neuroendocrinol, 2008 Nov. PMID 18761716
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables interleukin-1 receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-18 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-18 receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interleukin-18-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of type II interferon production IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
interleukin-18 receptor 1
Names
IL-18 receptor alpha
XP_005212515.1
XP_059747687.1

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    7165279..7194967
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005212458.5 → XP_005212515.1  interleukin-18 receptor 1 isoform X2

    See identical proteins and their annotated locations for XP_005212515.1

    UniProtKB/TrEMBL
    F1MJ29
    Related
    ENSBTAP00070047872.1, ENSBTAT00070078613.1
    Conserved Domains (5) summary
    cd00096
    Location:230 → 308
    Ig; Immunoglobulin domain
    smart00255
    Location:371 → 520
    TIR; Toll - interleukin 1 - resistance
    smart00410
    Location:220 → 310
    IG_like; Immunoglobulin like
    pfam13895
    Location:29 → 111
    Ig_2; Immunoglobulin domain
    cl11960
    Location:130 → 205
    Ig; Immunoglobulin domain

  2. XM_059891704.1 → XP_059747687.1  interleukin-18 receptor 1 isoform X1

    UniProtKB/TrEMBL
    F1MJ29
Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases
Research Materials