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EGR4 early growth response 4 [ Bos taurus (domestic cattle) ]

Gene ID: 407155, updated on 17-Aug-2024

Summary

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Official Symbol
EGR4provided by VGNC
Official Full Name
early growth response 4provided by VGNC
Primary source
VGNC:VGNC:28369
See related
BGD:BT18516; Ensembl:ENSBTAG00000024058
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (11158214..11161545)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene ALMS1 centrosome and basal body associated protein Neighboring gene N-acetyltransferase 8 (putative) Neighboring gene F-actin-capping protein subunit alpha-2-like Neighboring gene F-box protein 41 Neighboring gene chaperonin containing TCP1 subunit 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and characterization of the bovine EGR4 gene and evaluation as candidate gene for bovine spinal dysmyelination. Nissen PH, et al. Anim Genet, 2003 Apr. PMID 12648095
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
early growth response protein 4
Names
EGR-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040497.1 → NP_001035587.1  early growth response protein 4

    See identical proteins and their annotated locations for NP_001035587.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ293899
    UniProtKB/Swiss-Prot
    Q9GL31, Q9GL32
    Conserved Domains (4) summary
    COG5048
    Location:404 → 462
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:378 → 400
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:376 → 400
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:420 → 445
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    11158214..11161545
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005212481.5 → XP_005212538.1  early growth response protein 4 isoform X1

    UniProtKB/TrEMBL
    F1MAU9
    Related
    ENSBTAP00000033084.3, ENSBTAT00000033161.4
    Conserved Domains (4) summary
    COG5048
    Location:405 → 463
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:379 → 401
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:377 → 401
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:421 → 446
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9GL32.1 GenPept UniProtKB/Swiss-Prot:Q9GL32

Gene LinkOut

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Molecular Biology Databases
Research Materials