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BMPR1B bone morphogenetic protein receptor type 1B [ Bos taurus (domestic cattle) ]

Gene ID: 407128, updated on 5-Sep-2025
Official Symbol
BMPR1Bprovided by VGNC
Official Full Name
bone morphogenetic protein receptor type 1Bprovided by VGNC
Primary source
VGNC:VGNC:26525
See related
BGD:BT11289; EnsemblRapid:ENSBTAG00070003085
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
ALK6; BMP15; BMPRIB; BMPR-IB
Orthologs
human mouse all
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See BMPR1B in Genome Data Viewer
Location:
chromosome: 6
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (29371365..29820421, complement)

Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene unc-5 netrin receptor C Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene uncharacterized LOC132345563 Neighboring gene PDZ and LIM domain 5 Neighboring gene uncharacterized LOC132345564 Neighboring gene hematopoietic prostaglandin D synthase

Genomic Sequence:
NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Linkage mapping of the bovine bone morphogenetic protein receptor-1B (BMPR1B ) to chromosome 6. Kim JG, et al. Anim Genet, 2003 Aug. PMID 12873228
  2. microRNA-125b Regulates Apoptosis by Targeting Bone Morphogenetic Protein Receptor 1B in Yak Granulosa Cells. Yao Y, et al. DNA Cell Biol, 2018 Nov. PMID 30260685
  3. Expression of bone morphogenetic protein2 (BMP2), BMP4 and BMP receptors in the bovine ovary but absence of effects of BMP2 and BMP4 during IVM on bovine oocyte nuclear maturation and subsequent embryo development. Fatehi AN, et al. Theriogenology, 2005 Feb. PMID 15629804
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MicroRNA-125b regulates apoptosis by targeting BMPR1B in yak granulosa cells.
    Title: microRNA-125b Regulates Apoptosis by Targeting Bone Morphogenetic Protein Receptor 1B in Yak Granulosa Cells.
Submit: New GeneRIF Correction

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transforming growth factor beta receptor activity, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dorsal/ventral pattern formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
bone morphogenetic protein receptor type-1B
Names
bone morphogenetic protein receptor IB
bone morphogenetic protein receptor, type IB
NP_001098798.1
XP_005207776.1
XP_005207777.1
XP_010804274.1
XP_010804282.1
XP_010804289.1
XP_015327017.1
XP_024848830.1
XP_024848831.1
XP_024848834.1
XP_024848836.1
XP_024848840.1
XP_059743347.1
XP_059743348.1
XP_059743349.1
XP_059743351.1
XP_059743352.1
XP_059743353.1
XP_059743354.1
XP_059743355.1
XP_059743356.1
XP_059743357.1
XP_059743358.1
XP_059743359.1
XP_059743360.1
XP_059743361.1
XP_059743362.1
XP_059743363.1
XP_059743364.1
XP_059743365.1
XP_059743366.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105328.1 → NP_001098798.1  bone morphogenetic protein receptor type-1B

    See identical proteins and their annotated locations for NP_001098798.1

    Status: PROVISIONAL

    Source sequence(s)
    BC134547
    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6
    Related
    ENSBTAP00070004159.1, ENSBTAT00070007097.1
    Conserved Domains (2) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:30 → 106
    Activin_recp; Activin types I and II receptor domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    29371365..29820421 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059887383.1 → XP_059743366.1  bone morphogenetic protein receptor type-1B isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MKC5

  2. XM_059887375.1 → XP_059743358.1  bone morphogenetic protein receptor type-1B isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6

  3. XM_059887365.1 → XP_059743348.1  bone morphogenetic protein receptor type-1B isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LN35, A0A3Q1MKC5

  4. XM_059887382.1 → XP_059743365.1  bone morphogenetic protein receptor type-1B isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MKC5

  5. XM_059887380.1 → XP_059743363.1  bone morphogenetic protein receptor type-1B isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MKC5

  6. XM_059887381.1 → XP_059743364.1  bone morphogenetic protein receptor type-1B isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MKC5

  7. XM_059887379.1 → XP_059743362.1  bone morphogenetic protein receptor type-1B isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MKC5

  8. XM_059887376.1 → XP_059743359.1  bone morphogenetic protein receptor type-1B isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MKC5

  9. XM_010805980.4 → XP_010804282.1  bone morphogenetic protein receptor type-1B isoform X4

    See identical proteins and their annotated locations for XP_010804282.1

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6
    Conserved Domains (2) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:30 → 106
    Activin_recp; Activin types I and II receptor domain

  10. XM_059887371.1 → XP_059743354.1  bone morphogenetic protein receptor type-1B isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6

  11. XM_059887372.1 → XP_059743355.1  bone morphogenetic protein receptor type-1B isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6

  12. XM_059887370.1 → XP_059743353.1  bone morphogenetic protein receptor type-1B isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6

  13. XM_059887369.1 → XP_059743352.1  bone morphogenetic protein receptor type-1B isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LSA1, A0A3Q1MKC5
    Related
    ENSBTAP00070004149.1, ENSBTAT00070007082.1

  14. XM_010805972.4 → XP_010804274.1  bone morphogenetic protein receptor type-1B isoform X2

    See identical proteins and their annotated locations for XP_010804274.1

    UniProtKB/TrEMBL
    A0A3Q1LN35, A0A3Q1MKC5
    Conserved Domains (2) summary
    cd14219
    Location:222 → 526
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:54 → 130
    Activin_recp; Activin types I and II receptor domain

  15. XM_059887364.1 → XP_059743347.1  bone morphogenetic protein receptor type-1B isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LN35, A0A3Q1MKC5

  16. XM_024993072.2 → XP_024848840.1  bone morphogenetic protein receptor type-1B isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MKC5
    Conserved Domains (2) summary
    cd14219
    Location:180 → 484
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:28 → 88
    Activin_recp; Activin types I and II receptor domain

  17. XM_024993068.2 → XP_024848836.1  bone morphogenetic protein receptor type-1B isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6
    Conserved Domains (2) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:30 → 106
    Activin_recp; Activin types I and II receptor domain

  18. XM_024993062.2 → XP_024848830.1  bone morphogenetic protein receptor type-1B isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LN35, A0A3Q1MKC5
    Conserved Domains (2) summary
    cd14219
    Location:222 → 526
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:54 → 130
    Activin_recp; Activin types I and II receptor domain

  19. XM_059887373.1 → XP_059743356.1  bone morphogenetic protein receptor type-1B isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6

  20. XM_059887366.1 → XP_059743349.1  bone morphogenetic protein receptor type-1B isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LN35, A0A3Q1MKC5

  21. XM_059887377.1 → XP_059743360.1  bone morphogenetic protein receptor type-1B isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MKC5

  22. XM_024993066.2 → XP_024848834.1  bone morphogenetic protein receptor type-1B isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6
    Conserved Domains (2) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:30 → 106
    Activin_recp; Activin types I and II receptor domain

  23. XM_005207719.5 → XP_005207776.1  bone morphogenetic protein receptor type-1B isoform X1

    See identical proteins and their annotated locations for XP_005207776.1

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A0AAF6DLS3
    Related
    ENSBTAP00070004157.1, ENSBTAT00070007094.1
    Conserved Domains (3) summary
    smart00220
    Location:235 → 519
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14219
    Location:228 → 532
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:60 → 140
    Activin_recp; Activin types I and II receptor domain

  24. XM_015471531.3 → XP_015327017.1  bone morphogenetic protein receptor type-1B isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MKC5
    Conserved Domains (2) summary
    cd14219
    Location:180 → 484
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:28 → 88
    Activin_recp; Activin types I and II receptor domain

  25. XM_024993063.2 → XP_024848831.1  bone morphogenetic protein receptor type-1B isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LN35, A0A3Q1MKC5
    Related
    ENSBTAP00070004153.1, ENSBTAT00070007088.1
    Conserved Domains (2) summary
    cd14219
    Location:222 → 526
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:54 → 130
    Activin_recp; Activin types I and II receptor domain

  26. XM_059887374.1 → XP_059743357.1  bone morphogenetic protein receptor type-1B isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6

  27. XM_059887368.1 → XP_059743351.1  bone morphogenetic protein receptor type-1B isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LN35, A0A3Q1MKC5

  28. XM_010805987.4 → XP_010804289.1  bone morphogenetic protein receptor type-1B isoform X5

    See identical proteins and their annotated locations for XP_010804289.1

    UniProtKB/TrEMBL
    A0A3Q1MKC5
    Conserved Domains (2) summary
    cd14219
    Location:180 → 484
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:28 → 88
    Activin_recp; Activin types I and II receptor domain

  29. XM_005207720.5 → XP_005207777.1  bone morphogenetic protein receptor type-1B isoform X4

    See identical proteins and their annotated locations for XP_005207777.1

    UniProtKB/TrEMBL
    A0A3Q1MKC5, A7YWG6, F1N2N6
    Conserved Domains (2) summary
    cd14219
    Location:198 → 502
    STKc_BMPR1b; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IB
    pfam01064
    Location:30 → 106
    Activin_recp; Activin types I and II receptor domain

  30. XM_059887378.1 → XP_059743361.1  bone morphogenetic protein receptor type-1B isoform X5

    UniProtKB/TrEMBL
    A0A3Q1MKC5
Nucleotide Protein Strain
Heading Accession and Version

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