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MIR96 microRNA 96 [ Homo sapiens (human) ]

Gene ID: 407053, updated on 17-Jun-2024

Summary

Official Symbol
MIR96provided by HGNC
Official Full Name
microRNA 96provided by HGNC
Primary source
HGNC:HGNC:31648
See related
Ensembl:ENSG00000199158 MIM:611606; miRBase:MI0000098; AllianceGenome:HGNC:31648
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DFNA50; MIRN96; miR-96; miRNA96; hsa-mir-96
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR96 in Genome Data Viewer
Location:
7q32.2
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (129774692..129774769, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (131087826..131087903, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (129414532..129414609, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375501 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:129410483-129411346 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:129413073-129413934 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:129416778-129417624 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18633 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:129420163-129421008 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18634 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:129421855-129422700 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:129422701-129423545 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:129424259-129424770 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:129424771-129425281 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26633 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26634 Neighboring gene microRNA 182 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr7:129426816-129427326 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:129427327-129427837 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:129427838-129428347 Neighboring gene microRNA 183 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:129432262-129432762 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:129439452-129440063 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:129442015-129442516 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:129442517-129443016 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18636 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18637 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18638 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26635 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:129474501-129475160 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr7:129475895-129476430 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:129478138-129479337 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:129482500-129483326 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:129483327-129484153 Neighboring gene ubiquitin conjugating enzyme E2 H Neighboring gene NANOG hESC enhancer GRCh37_chr7:129519616-129520117 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26636 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:129585761-129586260 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:129588587-129589160 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:129589161-129589732 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26637 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18639 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18640

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA base-pairing translational repressor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of RISC complex IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_023385.1 RefSeqGene

    Range
    5246..5323
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. NR_029512.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC084864
    Related
    ENST00000362288.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    129774692..129774769 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    131087826..131087903 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)