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MIR184 microRNA 184 [ Homo sapiens (human) ]

Gene ID: 406960, updated on 23-Nov-2021

Summary

Official Symbol
MIR184provided by HGNC
Official Full Name
microRNA 184provided by HGNC
Primary source
HGNC:HGNC:31555
See related
Ensembl:ENSG00000207695 MIM:613146; miRBase:MI0000481
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EDICT; MIRN184; miR-184
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of target mRNAs. This microRNA represents the most abundant miRNA in the corneal and lens epithelia of the eye and has been shown to interfere with target binding by another miRNA, miR-205. Through regulation of the VEGF and Akt signaling pathways, this microRNA may inhibit corneal angiogenesis. Mutations in the seed region of this microRNA cause familial keratoconus with cataract, also known as EDICT syndrome. [provided by RefSeq, Mar 2017]
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Genomic context

See MIR184 in Genome Data Viewer
Location:
15q25.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (79209788..79209871)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (79502130..79502213)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene Ras protein specific guanine nucleotide releasing factor 1 Neighboring gene uncharacterized LOC105370917 Neighboring gene uncharacterized LOC107984750 Neighboring gene ANKRD34C antisense RNA 1 Neighboring gene heterogeneous nuclear ribonucleoprotein C pseudogene 3 Neighboring gene ankyrin repeat domain 34C

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_032125.1 RefSeqGene

    Range
    5001..5084
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. NR_029705.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC069082
    Related
    ENST00000384962.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    79209788..79209871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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