gsta.1 glutathione S-transferase, alpha tandem duplicate 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gsta.1provided by ZNC
Official Full Name: glutathione S-transferase, alpha tandem duplicate 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2720
See related: Ensembl:ENSDARG00000090228 AllianceGenome:ZFIN:ZDB-GENE-040426-2720
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: gstal; zgc:73173; wu:fk08d06
Summary: Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Is expressed in several structures, including epidermis; intestinal bulb primordium; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Orthologous to several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 13

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (843985..852506)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (699322..722215)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables glutathione transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glutathione transferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glutathione metabolic process	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: glutathione S-transferase, alpha tandem duplicate 1

Names: Gsta2; glutathione S-transferase, alpha-like

NP_998559.2

EC 2.5.1.18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213394.2 → NP_998559.2 glutathione S-transferase, alpha tandem duplicate 1

Status: VALIDATED

Source sequence(s)

AL929536

UniProtKB/TrEMBL

A0A8M6Z3S9, F1R4Z8

Related

ENSDARP00000058259.4, ENSDART00000058260.5