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usp5 ubiquitin specific peptidase 5 (isopeptidase T) [ Danio rerio (zebrafish) ]

Gene ID: 406618, updated on 22-Aug-2021

Summary

Official Symbol
usp5provided by ZNC
Official Full Name
ubiquitin specific peptidase 5 (isopeptidase T)provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2584
See related
Ensembl:ENSDARG00000014517
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fa06b0; wu:fi41g1; zgc:76990; wu:fa06b05; wu:fb36d11; wu:fc21h02; wu:fc61g08; wu:fi41g10
Orthologs
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Genomic context

See usp5 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
20
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (11965371..11986366, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (12074469..12095470, complement)
103 previous assembly Zv9 (GCF_000002035.4) 16 NC_007127.5 (13715378..13736539, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene CD4-1 molecule Neighboring gene CD4-2 molecule, tandem duplicate 2 Neighboring gene prolyl 3-hydroxylase 3 Neighboring gene guanine nucleotide binding protein (G protein), beta polypeptide 3a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables thiol-dependent deubiquitinase IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables thiol-dependent deubiquitinase IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
ubiquitin carboxyl-terminal hydrolase 5
Names
ubiquitin specific protease 5
NP_999920.2
XP_005173534.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214755.2NP_999920.2  ubiquitin carboxyl-terminal hydrolase 5

    See identical proteins and their annotated locations for NP_999920.2

    Status: PROVISIONAL

    Source sequence(s)
    BC097033
    UniProtKB/TrEMBL
    Q4V973
    Related
    ENSDARP00000124239.1, ENSDART00000148666.3
    Conserved Domains (5) summary
    COG5207
    Location:24831
    UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
    cd02658
    Location:325830
    Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cd14294
    Location:635678
    UBA1_UBP5_like; UBA1 domain found in ubiquitin carboxyl-terminal hydrolase UBP5, UBP13 and similar proteins
    cd14386
    Location:701742
    UBA2_UBP5; UBA2 domain found in ubiquitin carboxyl-terminal hydrolase 5 (UBP5)
    pfam02148
    Location:197270
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    11965371..11986366 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005173477.4XP_005173534.1  ubiquitin carboxyl-terminal hydrolase 5 isoform X1

    See identical proteins and their annotated locations for XP_005173534.1

    UniProtKB/TrEMBL
    Q1MT86
    Related
    ENSDARP00000036699.7, ENSDART00000029121.8
    Conserved Domains (5) summary
    COG5207
    Location:24850
    UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
    cd02658
    Location:325849
    Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cd14294
    Location:654697
    UBA1_UBP5_like; UBA1 domain found in ubiquitin carboxyl-terminal hydrolase UBP5, UBP13 and similar proteins
    cd14386
    Location:720761
    UBA2_UBP5; UBA2 domain found in ubiquitin carboxyl-terminal hydrolase 5 (UBP5)
    pfam02148
    Location:197270
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394956.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    35782..56543 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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