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chia.1 chitinase, acidic.1 [ Danio rerio (zebrafish) ]

Gene ID: 406323, updated on 2-Nov-2024

Summary

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Official Symbol
chia.1provided by ZNC
Official Full Name
chitinase, acidic.1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1994
See related
Ensembl:ENSDARG00000100635 AllianceGenome:ZFIN:ZDB-GENE-040426-1994
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
chit1; zgc:56053; wu:fb57c11; wu:fb66f12
Summary
Predicted to enable chitin binding activity and chitinase activity. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be active in extracellular region. Is expressed in intestinal bulb. Orthologous to human CHIT1 (chitinase 1) and OVGP1 (oviductal glycoprotein 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See chia.1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (23993365..23999226)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (23755508..23761369)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137490424 Neighboring gene neurofascin homolog (chicken) a Neighboring gene contactin 2 Neighboring gene chitinase, acidic.2 Neighboring gene chitinase, acidic.3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Spatial and temporal expression patterns of chitinase genes in developing zebrafish embryos. Koch BE, et al. Gene Expr Patterns, 2014 Mar. PMID 24418193
  2. Rearing Zebrafish on Black Soldier Fly (Hermetia illucens): Biometric, Histological, Spectroscopic, Biochemical, and Molecular Implications. Vargas A, et al. Zebrafish, 2018 Aug. PMID 29589997
  3. Partial Dietary Inclusion of Hermetia illucens (Black Soldier Fly) Full-Fat Prepupae in Zebrafish Feed: Biometric, Histological, Biochemical, and Molecular Implications. Zarantoniello M, et al. Zebrafish, 2018 Oct. PMID 29912648
  4. Wdr5-mediated H3K4me3 coordinately regulates cell differentiation, proliferation termination, and survival in digestive organogenesis. Zhang Z, et al. Cell Death Discov, 2023 Jul 5. PMID 37407577, Free PMC Article
  5. Thifluzamide induces the toxic effects on zebrafish (Danio rerio) via inhibition of succinate dehydrogenase (SDH). Yang Y, et al. Environ Pollut, 2020 Oct. PMID 32806454

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables chitin binding IEA
Inferred from Electronic Annotation
more info
  
enables chitinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
chitinase, acidic.1
Names
chia1
NP_998215.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213050.1 → NP_998215.1  chitinase, acidic.1 precursor

    See identical proteins and their annotated locations for NP_998215.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045887
    UniProtKB/TrEMBL
    B2GT22, Q7ZVF1
    Related
    ENSDARP00000139296.1, ENSDART00000172459.2
    Conserved Domains (3) summary
    cd02872
    Location:24 → 386
    GH18_chitolectin_chitotriosidase; This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active ...
    smart00494
    Location:407 → 455
    ChtBD2; Chitin-binding domain type 2
    smart00636
    Location:23 → 364
    Glyco_18; Glyco_18 domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    23993365..23999226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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