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Gnf1 Germ line transcription factor 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40607, updated on 28-Aug-2019

Summary

Official Symbol
Gnf1provided by FlyBase
Official Full Name
Germ line transcription factor 1provided by FlyBase
Primary source
FLYBASE:FBgn0004913
Locus tag
Dmel_CG1119
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG1119; Dmel\CG1119; DmRFC1; dRF-Cp140; dRFC140; Gnf-1; gnf1; GTF-1; gtf1; Gtf1; ONF-CAACAA; RF-C 140; RfC; RFC; rfc1; RFC1; RfC140; RFC140

Genomic context

See Gnf1 in Genome Data Viewer
Location:
82E2-82E2; 3-47.1 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4906622..4910081)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (732344..735803)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene labial associated factor Neighboring gene long non-coding RNA:CR45580 Neighboring gene Chondrocyte-derived ezrin-like domain containing protein Neighboring gene long non-coding RNA:CR45188

Genomic regions, transcripts, and products

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the Gnf1 gene: The Gnf1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding NAS
Non-traceable Author Statement
more info
PubMed 
DNA clamp loader activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA repair IEA
Inferred from Electronic Annotation
more info
 
DNA replication IEA
Inferred from Electronic Annotation
more info
 
DNA replication NAS
Non-traceable Author Statement
more info
PubMed 
dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
DNA replication factor C complex IEA
Inferred from Electronic Annotation
more info
 
DNA replication factor C complex NAS
Non-traceable Author Statement
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
germ line transcription factor 1
Names
CG1119-PA
CG1119-PB
Gnf1-PA
Gnf1-PB
Replication-factor-C 140kD subunit
germline transcription factor
replication factor C 140kD subunit

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    4906622..4910081
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001014605.3NP_001014605.1  germ line transcription factor 1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014605.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P35600
    Related
    FBpp0099511, FBtr0100159
    Conserved Domains (5) summary
    COG5275
    Location:151358
    COG5275; BRCT domain type II [General function prediction only]
    PRK04195
    Location:421969
    PRK04195; replication factor C large subunit; Provisional
    pfam00004
    Location:506633
    AAA; ATPase family associated with various cellular activities (AAA)
    pfam00533
    Location:232309
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam08519
    Location:764917
    RFC1; Replication factor RFC1 C terminal domain
  2. NM_079505.3NP_524229.1  germ line transcription factor 1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524229.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P35600
    Related
    FBpp0078478, FBtr0078837
    Conserved Domains (6) summary
    COG5275
    Location:151358
    COG5275; BRCT domain type II [General function prediction only]
    PRK04195
    Location:421947
    PRK04195; replication factor C large subunit; Provisional
    pfam00004
    Location:484611
    AAA; ATPase family associated with various cellular activities (AAA)
    pfam00533
    Location:232309
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam08519
    Location:742895
    RFC1; Replication factor RFC1 C terminal domain
    cl19912
    Location:605657
    DNA_pol3_delta; DNA polymerase III, delta subunit
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