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itgb1b.2 integrin, beta 1b.2 [ Danio rerio (zebrafish) ]

Gene ID: 405864, updated on 31-Aug-2021

Summary

Official Symbol
itgb1b.2provided by ZNC
Official Full Name
integrin, beta 1b.2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2598
See related
Ensembl:ENSDARG00000022689
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ES; EST; beta1tr; zgc:85632
Orthologs
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Genomic context

See itgb1b.2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (43638983..43653368, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (43719747..43734093)
103 previous assembly Zv9 (GCF_000002035.4) 2 NC_007113.5 (43670284..43684517)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene enhancer of polycomb homolog 1 (Drosophila) b Neighboring gene integrin, beta 1b.1 Neighboring gene uncharacterized LOC101884451 Neighboring gene NACHT, LRR and PYD domains-containing protein 3-like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Homology

Clone Names

  • MGC85632

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
contributes_to C-X3-C chemokine binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables collagen binding involved in cell-matrix adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables fibronectin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to laminin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in cell adhesion mediated by integrin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell-matrix adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in integrin-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in focal adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
part_of integrin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
integrin beta-1b.2; integrin, beta 1b.2
Names
ESTa
ESTb
beta1tr-1
beta1tr-2
beta1tr-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212928.2NP_998093.2  integrin beta-1b.2 precursor

    See identical proteins and their annotated locations for NP_998093.2

    Status: VALIDATED

    Source sequence(s)
    CABZ01058719, DQ440590
    UniProtKB/TrEMBL
    Q19U09
    Related
    ENSDARP00000036611.7, ENSDART00000037808.9
    Conserved Domains (1) summary
    pfam00362
    Location:34449
    Integrin_beta; Integrin, beta chain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    43638983..43653368 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479546.1XP_021335221.1  integrin, beta 1b.2 isoform X1

    Conserved Domains (2) summary
    pfam07974
    Location:518545
    EGF_2; EGF-like domain
    cl00057
    Location:3386
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
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