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gatad2ab GATA zinc finger domain containing 2Ab [ Danio rerio (zebrafish) ]

Gene ID: 405852, updated on 9-Sep-2025
Official Symbol
gatad2abprovided by ZNC
Official Full Name
GATA zinc finger domain containing 2Abprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2372
See related
Ensembl:ENSDARG00000006192 AllianceGenome:ZFIN:ZDB-GENE-040426-2372
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
gatad2a; zgc:85938; ns:zf-a189
Summary
Predicted to enable metal ion binding activity and sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of NuRD complex. Orthologous to human GATAD2A (GATA zinc finger domain containing 2A). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
human mouse all
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See gatad2ab in Genome Data Viewer
Location:
chromosome: 22
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 22 NC_133197.1 (18010647..18079354)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 22 NC_007133.7 (18316133..18384722)

Chromosome 22 - NC_133197.1Genomic Context describing neighboring genes Neighboring gene myocyte enhancer factor 2b Neighboring gene transmembrane protein 161A Neighboring gene uncharacterized LOC110438274 Neighboring gene microRNA 9-4 Neighboring gene uncharacterized LOC141380304 Neighboring gene uncharacterized LOC103909585 Neighboring gene uncharacterized LOC141380303 Neighboring gene YjeF N-terminal domain containing 3 Neighboring gene testis-specific serine kinase 6

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Rapid identification and isolation of zebrafish cDNA clones. Gong Z, et al. Gene, 1997 Nov 12. PMID 9409775
  2. Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of β-Cell Mass Deficits. O'Hare EA, et al. Mol Endocrinol, 2016 Apr. PMID 26963759, Free PMC Article
  3. Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. Thyme SB, et al. Cell, 2019 Apr 4. PMID 30929901, Free PMC Article
  4. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  5. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC85938

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of NuRD complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
GATA zinc finger domain containing 2Ab
Names
GATA zinc finger domain containing 2A

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212916.1 → NP_998081.1  GATA zinc finger domain containing 2Ab

    See identical proteins and their annotated locations for NP_998081.1

    Status: PROVISIONAL

    Source sequence(s)
    BC067707
    UniProtKB/TrEMBL
    Q6NW66
    Related
    ENSDARP00000031168.6, ENSDART00000033103.7
    Conserved Domains (2) summary
    pfam00320
    Location:399 → 434
    GATA; GATA zinc finger
    pfam16563
    Location:130 → 166
    P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133197.1 Reference GRCz12tu Primary Assembly

    Range
    18010647..18079354
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005170444.5 → XP_005170501.1  GATA zinc finger domain containing 2Ab isoform X1

    UniProtKB/TrEMBL
    A0A0R4IN87, A0A8M2BHS7
    Related
    ENSDARP00000135963.2, ENSDART00000160413.2
    Conserved Domains (3) summary
    pfam00320
    Location:522 → 557
    GATA; GATA zinc finger
    pfam05485
    Location:6 → 95
    THAP; THAP domain
    pfam16563
    Location:246 → 282
    P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2

  2. XM_005170446.5 → XP_005170503.1  GATA zinc finger domain containing 2Ab isoform X3

    UniProtKB/TrEMBL
    A0A8M2BHS5
    Conserved Domains (3) summary
    pfam00320
    Location:522 → 557
    GATA; GATA zinc finger
    pfam05485
    Location:6 → 95
    THAP; THAP domain
    pfam16563
    Location:246 → 282
    P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2

  3. XM_005170445.5 → XP_005170502.1  GATA zinc finger domain containing 2Ab isoform X2

    UniProtKB/TrEMBL
    A0A8M2BHS0
    Conserved Domains (3) summary
    pfam00320
    Location:515 → 550
    GATA; GATA zinc finger
    pfam05485
    Location:6 → 95
    THAP; THAP domain
    pfam16563
    Location:246 → 282
    P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2

  4. XM_068216268.1 → XP_068072369.1  GATA zinc finger domain containing 2Ab isoform X4

    UniProtKB/TrEMBL
    A0AB32TG41

  5. XM_005170448.6 → XP_005170505.1  GATA zinc finger domain containing 2Ab isoform X9

    UniProtKB/TrEMBL
    A0A2R8QD88, A0A8M2BI68
    Related
    ENSDARP00000150981.1
    Conserved Domains (2) summary
    pfam00320
    Location:406 → 441
    GATA; GATA zinc finger
    pfam16563
    Location:130 → 166
    P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2

  6. XM_068216270.2 → XP_068072371.1  GATA zinc finger domain containing 2Ab isoform X11

    UniProtKB/TrEMBL
    A0AB32TFV4

  7. XM_073936366.1 → XP_073792467.1  GATA zinc finger domain containing 2Ab isoform X12

  8. XM_068216269.2 → XP_068072370.1  GATA zinc finger domain containing 2Ab isoform X9

    UniProtKB/TrEMBL
    A0A2R8QD88, A0A8M2BI68

  9. XM_073936365.1 → XP_073792466.1  GATA zinc finger domain containing 2Ab isoform X11

    UniProtKB/TrEMBL
    A0AB32TFV4

  10. XM_073936364.1 → XP_073792465.1  GATA zinc finger domain containing 2Ab isoform X10

  11. XM_073936367.1 → XP_073792468.1  GATA zinc finger domain containing 2Ab isoform X12

  12. XM_005170447.6 → XP_005170504.2  GATA zinc finger domain containing 2Ab isoform X5

    UniProtKB/TrEMBL
    A0A8M2BHR2
    Related
    ENSDARP00000147496.1
    Conserved Domains (2) summary
    pfam00320
    Location:448 → 483
    GATA; GATA zinc finger
    pfam16563
    Location:172 → 208
    P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2

  13. XM_073936361.1 → XP_073792462.1  GATA zinc finger domain containing 2Ab isoform X7

  14. XM_073936360.1 → XP_073792461.1  GATA zinc finger domain containing 2Ab isoform X6

  15. XM_073936363.1 → XP_073792464.1  GATA zinc finger domain containing 2Ab isoform X8

RNA

  1. XR_012397345.1 RNA Sequence

  2. XR_012397346.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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