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bsk146 brain specific kinase 146 [ Danio rerio (zebrafish) ]

Gene ID: 405767, updated on 27-Mar-2024

Summary

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Official Symbol
bsk146provided by ZNC
Official Full Name
brain specific kinase 146provided by ZNC
Primary source
ZFIN:ZDB-GENE-060313-3
See related
Ensembl:ENSDARG00000099069 AllianceGenome:ZFIN:ZDB-GENE-060313-3
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sbk1
Summary
Enables protein kinase activity. Predicted to be involved in peptidyl-serine phosphorylation and peptidyl-threonine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoplasm. Is expressed in brain; eye; and immature eye. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 12
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (549600..558259, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (542336..552471, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene myosin phosphatase Rho interacting protein Neighboring gene si:dkey-94l16.4 Neighboring gene wu:fj29h11 Neighboring gene uncharacterized LOC108191688 Neighboring gene sulfotransferase family 2, cytosolic sulfotransferase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Identification of single-nucleotide polymorphism markers associated with cortisol response to crowding in rainbow trout. Liu S, et al. Mar Biotechnol (NY), 2015 Jun. PMID 25652693
  2. Expression and characterization of a brain-specific protein kinase BSK146 from zebrafish. Chou CM, et al. Biochem Biophys Res Commun, 2006 Feb 17. PMID 16403448
  3. Gene expression profiling in zebrafish embryos exposed to diclofenac, an environmental toxicant. De Felice B, et al. Mol Biol Rep, 2012 Mar. PMID 21643954
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BSK146 is a brain-specific protein kinase zebrafish
    Title: Expression and characterization of a brain-specific protein kinase BSK146 from zebrafish.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
serine/threonine-protein kinase SBK1
Names
SH3 domain-binding kinase 1
SH3-binding kinase 1
brain-specific protein kinase BSK146
protein kinase Bsk146
XP_009304631.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212841.2 → NP_998006.2  serine/threonine-protein kinase SBK1

    Status: VALIDATED

    Source sequence(s)
    BX000348
    UniProtKB/Swiss-Prot
    Q90ZY4
    UniProtKB/TrEMBL
    A0A8M3B753, B3DGG2
    Related
    ENSDARP00000132635.1, ENSDART00000168586.2
    Conserved Domains (1) summary
    cd13987
    Location:38 → 296
    STKc_SBK1; Catalytic domain of the Serine/Threonine kinase, SH3 Binding Kinase 1

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    549600..558259 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009306356.3 → XP_009304631.1  serine/threonine-protein kinase SBK1 isoform X1

    UniProtKB/TrEMBL
    B3DGG2
    Related
    ENSDARP00000134385.1, ENSDART00000158355.2
    Conserved Domains (1) summary
    cd13987
    Location:38 → 296
    STKc_SBK1; Catalytic domain of the Serine/Threonine kinase, SH3 Binding Kinase 1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q90ZY4.1 GenPept UniProtKB/Swiss-Prot:Q90ZY4

Gene LinkOut

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