Format

Send to:

Choose Destination

NPSR1-AS1 NPSR1 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 404744, updated on 25-Jan-2022

Summary

Official Symbol
NPSR1-AS1provided by HGNC
Official Full Name
NPSR1 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:22128
See related
Ensembl:ENSG00000197085 MIM:608596; AllianceGenome:HGNC:22128
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AAA1
Summary
This gene is located within a region that has been associated with asthma susceptibility. The locus is considered non-protein-coding based on lack of protein homology and a lack of experimental support for an encoded protein. Three alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2010]
Expression
Low expression observed in reference dataset See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See NPSR1-AS1 in Genome Data Viewer
Location:
7p14.3
Exon count:
9
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (34346512..34834331, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (34386124..34873943, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene BMP binding endothelial regulator Neighboring gene VISTA enhancer hs1336 Neighboring gene RNA, U6 small nuclear 438, pseudogene Neighboring gene neuropeptide S receptor 1 Neighboring gene ribosomal protein L7 pseudogene 31 Neighboring gene RNA, 7SL, cytoplasmic 132, pseudogene Neighboring gene non-SMC condensin I complex subunit D2 pseudogene 1 Neighboring gene uncharacterized LOC102724723 Neighboring gene dpy-19 like C-mannosyltransferase 1 Neighboring gene microRNA 548n Neighboring gene uncharacterized LOC105375228 Neighboring gene DPY19L2 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

EBI GWAS Catalog

Description
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
EBI GWAS Catalog

General gene information

Markers

Other Names

  • NPSR1 antisense RNA 1 (non-protein coding)
  • asthma-associated alternatively spliced gene 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021366.2 RefSeqGene

    Range
    81060..492820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. NR_015356.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs at both the 5' and 3' ends of the transcript compared to variant 1.
    Source sequence(s)
    AC005492, AY312365, BC031961
    Related
    ENST00000436945.4
  2. NR_033664.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    AC005582, AY312368, BX649082
    Related
    ENST00000419766.5
  3. NR_033665.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal exon compared to variant 1.
    Source sequence(s)
    AC005582, AY312369, BX649082

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    34346512..34834331 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_207283.1: Suppressed sequence

    Description
    NM_207283.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
  2. NM_207284.1: Suppressed sequence

    Description
    NM_207284.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
  3. NM_207285.1: Suppressed sequence

    Description
    NM_207285.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and it is a nonsense-mediated mRNA decay (NMD) candidate.
  4. NM_207286.1: Suppressed sequence

    Description
    NM_207286.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and it is a nonsense-mediated mRNA decay (NMD) candidate.
  5. NM_207287.1: Suppressed sequence

    Description
    NM_207287.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
  6. NM_207288.1: Suppressed sequence

    Description
    NM_207288.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and it is a nonsense-mediated mRNA decay (NMD) candidate.
  7. NM_207289.1: Suppressed sequence

    Description
    NM_207289.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
  8. NM_207290.1: Suppressed sequence

    Description
    NM_207290.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Support Center